dc.contributor.author | Rotich, Winnie C | |
dc.date.accessioned | 2014-11-28T12:15:51Z | |
dc.date.available | 2014-11-28T12:15:51Z | |
dc.date.issued | 2012 | |
dc.identifier.citation | Bachelor's degree in Pharmacy | en_US |
dc.identifier.uri | http://hdl.handle.net/11295/75640 | |
dc.description.abstract | Background: Erythropoietin Stimulating Agents (ESAs) provide relief and decrease blood
transfusion support among patients with anemia induced by chronic renal failure and cancer
chemotherapy. However. there is risk of cardiovascular and thrombovascular events occurring in
the course of treatment.
Objective: This study will seek to find out whether recommendations set out in Clinical
Oncology Practice Guidelines are followed at Kenyatta National Hospital (KNH) and what
monitoring parameters are considered in patients receiving ESAs.
Method: The study design will be hospital based descriptive retrospective study in which'
medical record files of patients to whom ESAs were dispensed from Kenyatta National Hospital
Main pharmacy and inpatient pharmacies between January 2011 and December 2011 will be
evaluated. The study variables will include patient demographics, diagnosis, indication for use of
ESAs. the dosage. frequency, duration of therapy, laboratory parameters including Hb level and
time to reach target Hb. Data collected will be analyzed and summarized using tables, graphs and
summary statistics.
Intended use of results: It is hoped that the findings from this study will be used to improve the
use of ESAs at KNH in order to achieve maximum benefit to the patients. The results will also
be useful in developing an institutional protocol for the use of ESAs.
Results: The studies have shown that the Lise of erythropoietin in KNH is predominantly in renal
patients (95.93%) and a very small percentage use in oncology (4.07%). It has enabled us to
settle on a conclusion over the debate on whether ESAs are used rationally or irrationally. It is
used irrationally due to poor patient monitoring and follow up. Further work needs to be done to
improve on the use. | en_US |
dc.language.iso | en | en_US |
dc.publisher | University of Nairobi | en_US |
dc.title | An assessment of the use of erythropoiet in stimulating agents in Kenyatta national hospital | en_US |
dc.type | Thesis | en_US |
dc.description.department | a
Department of Psychiatry, University of Nairobi, ; bDepartment of Mental Health, School of Medicine,
Moi University, Eldoret, Kenya | |
dc.type.material | en_US | en_US |