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dc.contributor.authorCranmer, LM
dc.contributor.authorKanyugo, M
dc.contributor.authorLohman-Payne, B
dc.contributor.authorTapia, K
dc.contributor.authorJohn-Stewart, GC
dc.date.accessioned2015-01-13T12:57:23Z
dc.date.available2015-01-13T12:57:23Z
dc.date.issued2015-12
dc.identifier.citationInt J Tuberc Lung Dis. 2015 ;19(2):141-3en_US
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pubmed/25574910
dc.identifier.urihttp://hdl.handle.net/11295/79753
dc.description.abstractTuberculosis (TB) cellular immune responses were examined in the breast milk of human immunodeficiency virus infected mothers using the T-SPOT(®). TB interferon-gamma release assay (IGRA). Positive TB interferon-gamma (IFN-γ) responses were detected in 6 of 8 (75%) valid breast milk assays. Among 7 mothers with paired breast milk and blood assays, TB IFN-γ responses were higher in breast milk than in blood (P = 0.02). The magnitude of TB IFN-γ responses in maternal breast milk and blood were correlated. Elucidating the influence of TB immune responses in breast milk on infant TB susceptibility and immunity may inform future maternal TB vaccine strategiesen_US
dc.language.isoenen_US
dc.publisherUniversity of Nairobien_US
dc.titleTuberculosis interferon-gamma responses in the breast milk of human immunodeficiency virus infected mothers.en_US
dc.typeArticleen_US
dc.type.materialenen_US


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