Faculty of Health Sciences (FHS): Recent submissions
Now showing items 1701-1720 of 4298
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Application of in vitro – in vivo correlation (ivivc) as a predictive tool for bio-equivalence studies for generic paracetamol immediate release tablets.
(University Of Nairobi, 2016)xix ABSTRACT Medicines regulatory authorities among developing countries, particularly in Africa, are increasingly demanding that data on bioequivalence studies should be included when applying for marketing authorization ... -
Dental age estimation in children attending a university dental hospital.
(University of Nairobi, 2016)Background: There are various circumstances when the chronological age of a child needs to be verified but due to lack of legally approved documentary evidence, age has to be conventionally estimated. Determination of ... -
Factors associated with patient waiting time at a medical outpatient clinic: a case study of University of Nairobi health services.
(University of Nairobi, 2016)Background: Excessive long waiting time in outpatient clinics in Africa is a constant challenge for patients and the health providers of these facilities. Prolonged waiting times are associated with poor adherence to ... -
Knowledge, attitude and practices of mothers with malnourished children less than thirty six months regarding breastfeeding and complementary feeding in Kitui County Hospital.
(University of Nairobi, 2013)Introduction: Under nutrition remains one of the most common causes of morbidity and mortality among children globally. It causes about 3.5 million deaths, with 35% of the disease burden being in children under five years. ... -
Effect of variable high fat diets on heart rate variability and selected modifiable cardiovascular risk factors.
(University of Nairobi, 2013)Background: Cardiovascular diseases are on the rise particularly in developing countries and multiple factors are responsible this alarming trend. Non-ideal dietary fats adversely affect the traditional cardiovascular risk ... -
Comparison of placenta structure in preterm deliveries between HIV infected and uninfected women in Kenya.
(Kiragu H, Kamucha G, Mwangi E. A Robust Magnetic Resonance Imaging Method Based on Compressive Sampling and Clustering of Sparsifying Coefficients. Limassol, Cyprus ; 2016., 2015)Background: Preterm birth (PTB) is a major cause of infant morbidity and mortality in developing countries. The underlying structural mechanisms by which PTB occur are largely unknown. Whereas the association between ... -
Quality of care in women of reproductive age with epilepsy and knowledge of residents on women’s issues in epilepsy at the Kenyatta National Hospital.
(University of Nairobi, 2016)Background. Epilepsy is a common neurological disorder affecting men and women equally. However, its impact on women involves unique gender issues related to hormone effects on seizure control, seizure and drug effects ... -
Adherence to antiretroviral therapy among HIV infected adolescents at Kangundo District Hospital.
(University of Nairobi, 2016)Background: World Health Organization (WHO) defines adolescents as those aged 10–19 years. They represent 25% of the population in sub-Saharan Africa. Eighty-two percent of the estimated 2.1 million adolescents aged 10–19 ... -
A comparative study of transvaginal ultrasound scan and digital vaginal examination in prediction of preterm delivery at 32 to 36 weeks in Kitui District Hospital.
(University of Nairobi, 2016)Introduction: Preterm labour occurs when regular uterine contractions associated with cervical shortening and dilatation occurs before 37 weeks of gestation. Preterm deliveries are those that occur at less than 37 weeks ... -
Development and validation of a stability indicating liquid chromatographic method for the analysis of rufinamide bulk material and dosage forms
(University of Nairobi, 2016-11)Rufinamide is a triazole anti-epileptic used together with other medications/therapies in the management of seizures linked to Lennox Gastaut Syndrome (LGS) and various epileptic disorders in adults, as well as in children ... -
Correlation between receptor status and the presence of axillary lymph node metastasis in breast cancer in Kenyatta National Hospital.
(University of Nairobi, 2016)Background: Breast cancer is the second most common malignancy in Kenyan women. Breast cancer survival is linked to early detection, timely and appropriate treatment. Furthermore, survival is dependent on stage and ... -
Tumour differentiation and high risk histology features as prognostic factors among patients with retinoblastoma at Kenyatta National Hospital and Presbyterian church of East Africa Kikuyu Hospital.
(University of Nairobi, 2016)1. BACKGROUND The management protocol for retinoblastoma (RB) post-enucleation, recommends adjuvant treatment for patients exhibiting high risk histopathology features. The degree of tumour differentiation in RB has not ... -
Organizational practices influencing availability of essential medicines at hospitals in Nairobi county
(University of Nairobi, 2016-12)Background Sub-optimal access to affordable essential medicines in developing countries is mainly attributable to poor availability of these medicines, mainly in the public health sector. Easy access to prescribed medicines ... -
Utility Of P16ink4A/ki-67 immunostain as an adjunct to conventional pap smear for the diagnosis of cervical lesions among women living with Hiv at comprehensive care clinic in KNH, Kenya.
(University of Nairobi, 2016)Background: The current cervical cancer screening methods pose limitations. Since use of biomarkers has shown efficiency, there is need for a disease specific biomarker such as the p16INK4a /ki-67 Immunocytochemical (ICC) ... -
Four year trend and follow up of women aged more than 15 years with reproductive tract cancers in Kenyatta National Hospital (2008-2011).
(University of Nairobi, 2016)Background: Female reproductive tract malignancies involve the ovary, fallopian tubes, uterus corpus, choriocarcinoma, cervix, vagina, vulva and skin overlying the genital. In a study done in Kenyatta National Hospital in ... -
Depression in mothers of children with severe acute malnutrition admitted in Kenyatta National Hospital Peadiatric Wards.
(University of Nairobi, 2016)BACKGROUND Depression is the leading cause of disability worldwide. In women it is a significant cause of disease related disability. Globally, an estimated 350 million people suffer from depression. The prevalence of ... -
Knowledge and practice on safe handling of cytotoxic drugs among health care workers at Kenyatta National Hospital.
(University of Nairobi, 2016)Background: Cytotoxic drugs are carcinogenic, mutagenic and teratogenic. Improper handling and use of these drugs leads to occupational health hazards among workers in cancer management settings. No study has been published ... -
Assessment of knowledge of and adherence to the recommended intrapartum obstetric guidelines for PMTCT of HIV by health workers at Mbagathi District Hospital, Nairobi.
(University of Nairobi, 2016-04)Introduction: In Kenya, 37,000-42,000 infants are infected with HIV yearly due to mother-to-child transmission (MTCT). Even though intra-partum obstetric guidelines for PMTCT of have been developed and ratified by the ... -
Bone mineral density abnormalities in HIV infected patients and hiv negative respondents at Mbagathi Hospital using calcaneal quantitative ultrasound.
(University of Nairobi, 2016)Background Osteoporosis is a systemic skeletal disorder characterized by low bone mass and micro-architectural deterioration of bone tissue, with a consequent increase in bone fragility and fracture. Kenya has an estimated ... -
Pattern of superficial surgical site infection after elective orthopaedic surgery at Kikuyu P.C.E.A Orthopaedic Rehabilitation Center.
(University of Nairobi, 2016)Background: Surgical site infection (SSI) is the commonest complication of surgery with prevalence rates as high as 20% in the USA. 10 SSIs are a leading cause of morbidity and mortality as well as increase in economic ...