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Now showing items 11-20 of 32
Acaricide resistance in livestock ticks infesting cattle in Africa: Current status and potential mitigation strategies
(University of Nairobi, 2022-05)
In many African countries, tick control has recently been the responsibility of resource-poor farmers rather than central government veterinary departments. This has led to an increase in acaricide resistance, threatening ...
Sensitivity Analysis of a Transmission Interruption Model for the Soil-Transmitted Helminth Infections in Kenya
(University of Nairobi, 2022-03)
As the world rallies toward the endgame of soil-transmitted helminths (STH) elimination by the year 2030, there is a need for efficient and robust mathematical models that would enable STH programme managers to target the ...
Antibacterial Secondary Metabolites From Vernonia Auriculifera Hiern (Asteraceae) Against Mdr Phenotypes
(University of Nairobi, 2022)
Purification of the aerial parts of Vernonia auriculifera Hiern
afforded steroids (1–2), flavonoids (3–5), and polyalcohol (6).
Their structures were determined using spectral evidences as well
as by comparison with ...
Integrating Stakeholder Preferences Into Ecosystem Services Mapping in Yala Wetland, Kenya
(University of Nairobi, 2022)
Wetlands such as the Yala swamp in Kenya are among the most important and increasingly
threatened ecosystems globally due to their ecological significance and complexity, and the
importance of the ecosystem services (ES) ...
Earth’s Sediment Cycle During the Anthropocene
(University of Nairobi, 2022)
The global sediment cycle is a fundamental feature of the Earth system, balancing
competing factors such as orogeny, physical–chemical erosion and human action. In this Review,
values of the magnitudes of several sources ...
Membrane Permeabilization and Antimicrobial Activity of Recombinant Defensin-d2 and Actifensin Against Multidrug-resistant Pseudomonas Aeruginosa and Candida Albicans
(University of Nairobi, 2022)
Antimicrobial resistance requires urgent efforts towards the discovery of active antimicrobials, and the development of strategies to sustainably produce them. Defensin and defensin-like antimicrobial peptides (AMPs) are ...
Optimised germination protocol for jackfruit seeds and evaluation of methods for extraction of DNA suitable for genetic analysis
(JPPS, 2022-08-18)
Jackfruit (Artocarpus heterophyllus) is an underutilised plant that is promising in curbing food and nutritional security in sub-Saharan Africa. However, high level of secondary metabolites in its tissues significantly ...
Rare Alleles and Signatures of Selection on the Immunodominant Domains of Pfs230 and Pfs48/45 in Malaria Parasites From Western Kenya
(University of Nairobi, 2022)
Background: Malaria elimination and eradication efforts can be advanced by including transmission-blocking or reducing vaccines (TBVs) alongside existing interventions. Key transmission-blocking vaccine candidates, such ...
Environmental Distribution and Risk of Exposure of Heavy Metal Pollutants From Lolgorian Artisanal Gold Mining in Kenya
(University of Nairobi, 2022)
The aim of the study was to assess the distribution of heavy metals in the environmental compartments from artisanal and small-scale gold mining (ASGM) activities from Lolgorian, Kenya. The investigation was carried out ...
Cytotoxic Alkaloids From the Root of Zanthoxylum Paracanthum (Mildbr) Kokwaro
(University of Nairobi, 2022)
Chemical investigation of the root of Zanthoxylum paracanthum afforded 1 new alkamide derivative, (2E,4E)-6-oxo-N-isobutyldeca-2,4-dienamide (1) together with 10 known congeners including one phenolic amide (2), four ...