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Antiplasmodial and cytotoxic activities of the constituents of turraea robusta and turraea nilotica
(University of Nairobi, 2015-08)
Ethnopharmacological relevance
Turraea robusta and Turraea nilotica are African medicinal plants used for the treatment of a wide variety of diseases, including malaria. The genus Turraea is rich in limonoids and other ...
Antiplasmodial, cytotoxicity and phytochemical constituents of four maytenus species used in traditional medicine in Kenya
(2017)
Background: In Kenya, several species of the genus Maytenus are used in traditional medicine to treat many diseases including malaria. In this study, phytochemical constituents and extracts of Maytenus undata, M. ...
8-Methoxyneorautenol and radical scavenging flavonoids from Erythrina abyssinica
(2009)
A new pterocarpan (named 8-methoxyneorautenol) was isolated from the acetone extract of the
root bark of Erythrina abyssinica. In addition, the known isoflavonoid derivatives eryvarin L, erycristagallin and
shinpterocarpin ...
(+)-Tephrodin - A New Flavone from Tephrosia purpurea
(1972)
Tephrosia species are widely used
in East African traditional medicinal
practice to treat various infectious
diseases. In our continued search
for antiplasmodial agents from
Tephrosia species found in Kenya a
new ...
Terpurinflavone: An antiplasmodial flavone from the stem of Tephrosia Purpurea
(Elsevier B.V., 2011)
The stem extract of Tephrosia purpurea showed anti plasmodial activity against the D6 (chloroquinesensitive)
and W2 (chloroquine-resistant) strains of Plasmodium /aldparum with 1(50 values of
10.47 ± 2.22 f.Lg/mland 12.06 ...
Antiplasmodial and antileishmanial flavonoids from Mundulea sericea
(University of Nairobi, 2020)
Five known compounds (1-5) were isolated from the extract of Mundulea sericea leaves. Similar investigation of the roots of this plant afforded an additional three known compounds (6-8). The structures were elucidated using ...
A new C-C linked benzophenathridine-2-quinoline dimer, and the antiplasmodial activity of alkaloids from Zanthoxylum holstzianum
(University of Nairobi, 2023)
The CH2Cl2/MeOH (1:1) extract of Zanthoxylum holstzianum stem bark showed good antiplasmodial activity (IC50 2.5 ± 0.3 and 2.6 ± 0.3 µg/mL against the W2 and D6 strains of Plasmodium falciparum, respectively). From the ...