Now showing items 21-22 of 22

    • Trends in HIV -1 Incidence in a Cohort of Prostitutes in Kenya: Implications for HIV -1 Vaccine Efficacy Trials 

      Baeten, JM; Richardson, BA; Martin, HL; Nyange, PM; Lavreys, L; Ngugi, Elizabeth N; Mandaliya, K; Ndinya-Achola, JO; Bwayo, JJ; Kreiss, JK (Department of Community Health, University of Nairobi, 2000)
      Background: Accurate predictions of HIV-I incidence in potential study populations are essential for designing HIV-I vaccine efficacy trials. Lillie information is available on the estimated incidence of HIV-I in such ...
    • Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet? 

      Marsh, Kevin; Ward, Steve; Winstanley, Peter; Gilbert, Kokwaro; Nduati, Eunice; Ochong, Edwin; Nzila, Alexis (Department of Pharmaceutics and Pharmacy Practice, 2005)
      Resistance to the antifolate sulfadoxine–pyrimethamine (SP), the current mass-treatment antimalarial drug, is associated with selection of point mutations in dihydrofolate reductase and dihydropteroate synthase. Among these ...