Browsing Faculty of Health Sciences (FHS) by Subject "antiretroviral therapy; drug-resistant mutation; human immunodeficiency virus; human leukocyte antigen; next-generation sequencing technology."
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High Level of Pre-Treatment HIV-1 Drug Resistance and Its Association with HLA Class I-Mediated Restriction in the Pumwani Sex Worker Cohort
(University of Nairobi, 2022-01)Background: We analyzed the prevalence of pre-antiretroviral therapy (ART) drug resistance mutations (DRMs) in a Kenyan population. We also examined whether host HLA class I genes influence the development of pre-ART ...