Browsing Faculty of Health Sciences (FHS) by Subject "apoptosis"

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    • Catha edulis (khat) induces cell death by apoptosis in leukemia cell lines 

      O K, Vintermyr; A C, Johannessen; G W, Francis; B T, Gjertsen; E, Dimba (Department of Oral/Maxillofacial Surgery, Oral Medicine/Pathology, Oral/Maxillofacial Radiology, 2003)
      Khat is the Celastraceus edulis plant, a flowering evergreen tree or large shrub, which grows in the Horn of Africa and southwestern Arabia. Khat use has been associated with development of oral cancer, but its molecular ...

    • Khat (Catha edulis)-induced apoptosis is inhibited by antagonists of caspase-1 and -8 in human leukaemia cells. 

      Dimba, EA; Gjertsen, BT; Bredholt, T; Fossan, KO; Costea, DE; Francis, GW; Johannessen, AC; Vintermyr, OK (University of Nairobi,Department of Oral and Maxillofacial Radiology, 2004-11)
      Khat chewing is a widespread habit that has a deep-rooted sociocultural tradition in Africa and the Middle East. The biological effects of khat are inadequately investigated and controversial. For the first time, we show ...