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Now showing items 11-17 of 17
Epidemiological and clinical characteristics of patients hospitalised with COVID-19 in Kenya: a multicentre cohort study
(University of Nairobi, 2022-05)
Objectives: To assess outcomes of patients admitted to hospital with COVID-19 and to determine the predictors of mortality.
Setting: This study was conducted in six facilities, which included both government and privately ...
An Empiric Tool to Identify Kenyans Living With Hiv Who Will Have Unsuppressed Viremia 18 Months Following Treatment Initiation to Guide Differentiated Care Models
(University of Nairobi, 2022)
Background: With the global push towards universal access to Antiretroviral Treatment (ART), patient numbers are increasing, further straining already under-resourced healthcare systems in sub-Saharan Africa. A simple ...
Rethinking the syndemic of tuberculosis and dysglycaemia: a Kenyan perspective on dysglycaemia as a neglected risk factor for tuberculosis
(University of Nairobi, 2023)
Background: The END TB 2035 goal has a long way to go in low-income and low/middle-income countries (LICs and LMICs) from the perspective of a non-communicable disease (NCD) control interaction with tuberculosis (TB). The ...
Prevalence and functional profile of SARS-CoV-2 T cells in asymptomatic Kenyan adults
(University of Nairobi, 2023)
BackgroundSARS-CoV-2 infection in Africa has been characterized by a less severe disease profile than what has been observed elsewhere, but the profile of SARS-CoV-2-specific adaptive immunity in these mainly asymptomatic ...
Age and CD4+ T cell counts are inversely associated with HIV drug resistance mutations in treatment naive female sex workers
(University of Nairobi, 2023)
The increasing prevalence of human immunodeficiency virus (HIV) drug resistance mutations (HIVDRM) in untreated seropositive persons has consequences for future treatment options. This is extremely important in key populations ...
Hepatitis B status and associated factors among participants screened for simulated HIV vaccine efficacy trials in Kenya and Uganda
(University of Nairobi, 2023)
Introduction: Hepatitis B (HBV) prevalence remains high in Sub Saharan Africa and among some key populations such as those with continued exposure through sexual contact. We assessed the HBV status among potential participants ...
Temporal trends and transmission dynamics of pre-treatment HIV-1 drug resistance within and between risk groups in Kenya, 1986-2020
(University of Nairobi, 2024)
Background: Evidence on the distribution of pre-treatment HIV-1 drug resistance (HIVDR) among risk groups is limited in Africa. We assessed the prevalence, trends and transmission dynamics of pre-treatment HIVDR within and ...