Faculty of Health Sciences (FHS): Recent submissions
Now showing items 1161-1180 of 10384
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Evaluation of liposomal nanocarriers loaded with ETB receptor agonist, IRL-1620, using cell-based assays.
(University of Nairobi, 2016)One common feature of most neurodegenerative diseases, including Alzheimer's disease (AD) and stroke, is the death of neuronal cells. Neuronal cell death is associated with apoptosis, generation of reactive oxygen species ... -
Building Learning Health Systems to Accelerate Research and Improve Outcomes of Clinical Care in Low- and Middle-Income Countries
(University of Nairobi, 2016)Achieving universal coverage that supports high-quality care will require that health systems are designed to integrate the delivery of health services with the generation of new knowledge about the effectiveness of these ... -
Evaluation of a training on DVD pneumococcal conjugate vaccine for Kenyan EPI healthcare workers
(University of Nairobi, 2016)Background: The Kenyan Ministry of Public Health and Sanitation was the first in Africa to introduce the new 10‑valent Pneumococcal Conjugate Vaccine, PCV-10, in 2011. For successful implementation and to avoid adverse ... -
A comparative study of the quality of care and glycemic control among ambulatory type 2 diabetes mellitus clients, at a tertiary referral hospital and a regional hospital in central Kenya
(University of Nairobi, 2016)Background Peripheral public health facilities remain the most frequented by the majority of the population in Kenya; yet remain sub-optimally equipped and not optimized for non-communicable diseases care. Design and ... -
Significance bias: an empirical evaluation of the oral health literature
(University of Nairobi, 2016)Background The tendency to selectively report “significant” statistical results (file-drawers effect) or run selective analyses to achieve “significant” results (data-dredging) has been observed in many scientific fields. ... -
Building capacity in implementation science research training at the University of Nairobi
(University of Nairobi, 2016)Background Health care systems in sub-Saharan Africa, and globally, grapple with the problem of closing the gap between evidence-based health interventions and actual practice in health service settings. It is essential ... -
Molecular characterization of human coronaviruses and their circulation dynamics in Kenya, 2009-2012.
(University of Nairobi, 2016)Background Human Coronaviruses (HCoV) are a common cause of respiratory illnesses and are responsible for considerable morbidity and hospitalization across all age groups especially in individuals with compromised ... -
Genotyping of enteroviruses isolated in Kenya from pediatric patients using partial VP1 region
(University of Nairobi, 2016)Enteroviruses (EV) are responsible for a wide range of clinical diseases in humans. Though studied broadly in several regions of the world, the genetic diversity of human enteroviruses (HEV) circulating in the sub-Saharan ... -
Distinct genital tract hiv-specific antibody profiles associated with tenofovir gel
(University of Nairobi, 2016)The impact of topical antiretrovirals for pre-exposure prophylaxis on humoral responses following HIV infection is unknown. Using a binding antibody multiplex assay, we investigated HIV-specific IgG and IgA responses to ... -
The prevalence of TEM and SHV genes among extended-spectrum beta-lactamase-producing klebsiella pneumoniae and escherichia coli
(University of Nairobi, 2016)Background: Antimicrobial resistance to cephalosporin, penicillin and aztreonam is mediated by Extended-Spectrum Beta-Lactamases (ESBL) via hydrolysis of antibiotics. The most common bacteria associated with ESBL among the ... -
A Single-Arm, Proof-Of-Concept Trial of Lopimune (Lopinavir/Ritonavir) as a Treatment for HPV-Related Pre-Invasive Cervical Disease
(University of Nairobi, 2016)Background Cervical cancer is the most common female malignancy in the developing nations and the third most common cancer in women globally. An effective, inexpensive and self-applied topical treatment would be an ideal ... -
Exploring the intricacies of contemporary Phd research process
(University of Nairobi, 2015)The process leading to a PhD degree award has evolved over a period of many years to become what it is today. There are important considerations and emphasis continually being placed by the degree awarding authorities on ... -
Applying Bayesian Model to Predict Socio-demographic and Occlusal Determinants of Early Childhood Caries (ECC)
(University of Nairobi, 2017)Objective: To use the Bayesian statistical Model approach to predict the most important socio-demographic and occlusal factors pertinent to high prevalence of ECC. Material and Methods: A questionnaire and an oral ... -
Association Of Fever And Diarrhea With Infant Teething Among Mothers Attending Two Health Centres In Nairobi
(University of Nairobi, 2015)Introduction: Many global communities associate infant teething with diarrhea and fever. The perception that infant teething is a cause of pain and discomfort is often shared by both mothers/care- givers ... -
Preliminary Outcome of Case Series of the Management of Unilateral and Bilateral Craniomandibular Ankylosis in Kenya
(University of Nairobi, 2015)Temporomandibularmandibular ankylosis also known as the craniomandibular joint (CMJ) ankylosis is a Greek terminology that means “stiff joint”. It is most commonly associated with trauma and to a lesser extent middle ear ... -
Determinants of pneumococcal conjugate vaccine uptake among children attending immunisation services at Kenyatta national hospital, Nairobi, Kenya
(University of Nairobi, 2016)Objective: To establish the determinants of pneumococcal conjugate vaccine uptake among children brought to Kenyatta National Hospital. Design: A cross-sectional hospital-based quantitative and qualitative study Setting: ... -
Selection of direct restorative and rooting filling materials by Kenyan dentists in 2014
(University of Nairobi, 2016)Objectives: To establish the categories of direct restorative and root filling materials used by dentists in Kenya as well as the factors considered in their selection. Design: A descriptive cross-sectional study. Setting: ... -
Early growth in preterm infants after hospital discharge in rural Kenya: longitudinal study
(University of Nairobi, 2016)Introduction Prematurity is the single most important cause of mortality during the neonatal period. The early growth of these infants has been shown to be a predictor of their later growth and neurodevelopmental outcomes. ... -
Assessment of parents’ perception of quality of pediatric oncology inpatient care at Kenyatta National Hospital
(University of Nairobi, 2017)OBJECTIVE: Adequate knowledge of parents' perception of quality of pediatric cancer care helps to identify the areas of care improvement which would contribute to disease outcome in regard to the quality of life and ... -
A prospective study of intimate partner violence as a risk factor for detectable plasma viral load in hiv-positive women engaged in transactional sex in Mombasa, Kenya.
(University of Nairobi, 2016)We conducted a prospective cohort study to evaluate intimate partner violence (IPV) as a risk factor for detectable plasma viral load in HIV-positive female sex workers (FSWs) on antiretroviral therapy (ART) in Kenya. IPV ...