Faculty of Health Sciences (FHS): Recent submissions
Now showing items 1481-1500 of 10385
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Response of Plasmodium falciparum to dihydrofolate reductase inhibitors in Malindi, Kenya
(University of Nairobi, 1985)The response of Plasmodium falciparum isolates to dihydrofolate reductase inhibitors (DHFRI) was examined in Malindi, Kenya. All 20 infected children treated with pyrimethamine/sulphadoxine responded. In contrast, after ... -
Antagonism of sulfadoxine and pyrimethamine antimalarial activity in vitro by p-aminobenzoic acid, p-aminobenzoylglutamic acid and folic acid
(University of Nairobi, 1985-01)The activity of pyrimethamine and sulfadoxine against two strains of Plasmodium falciparum has been studied in vitro by a radioisotopic technique. Low level antagonism of pyrimethamine resulted from the inclusion of ... -
Knowledge, Attitude and Practice of Health-Care Waste Management and Associated Health Risks in the Two Teaching and Referral Hospitals in Kenya
(University of Nairobi, 2012-12)Hazardous health-care waste poses a great danger to public health and the environment if it is not properly managed. There is need for health-care workers involved in its management to understand the integral link between ... -
Ischemic Cortical Stroke in a Kenyan Referral Hospital
(University of Nairobi, 2015)Background: The pattern of stroke displays ethnic and geographical variations. In Sub-Saharan Africa there is scarcity of data from Eastern and Central Africa. Objective: To describe the characteristics of patients with ... -
Using health provider insights to inform pediatric HIV disclosure: a qualitative study and practice framework from Kenya
(University of Nairobi, 2014)Optimal pediatric HIV disclosure impacts illness and developmental experiences while improving access to timely treatment. However, disclosure rates in high HIV prevalence countries remain low and there are limited data ... -
Heterogeneity of Smooth Muscle Cells in Tunica Media of Aorta in Goat (Capra hircus)
(University of Nairobi, 2014)Knowledge of the characteristics of vascular smooth muscle cells is important in understanding physicomechanical properties, functions, mechanisms of development, remodelling, regeneration of blood vessels, development and ... -
Schistosomiasis of spinal cord.
(University of Nairobi, 1977)The case is reported of a 14-month-old child admitted to hospital in Kenya with a 6-week history of progressive weakness of both lower limbs and urinary incontinence following an acute febrile illness. A thoraco-lumbar ... -
Leishmania donovani parasites in the nasal secretions, tonsillopharyngeal mucosa, and urine centrifugates of visceral leishmaniasis patients in Kenya.
(University of Nairobi, 1993)In the early 1930s, investigators of visceral leishmaniasis stated that Leishman-Donovan bodies are found in body fluids of kala-azar patients, for example, in urine, feces, semen, and nasal and pharyngeal secretions. Based ... -
Outcome of the first medicines utilization research in Africa group meeting to promote sustainable and rational medicine use in Africa.
(University of Nairobi, 2015)The second Medicines Utilization Research in Africa (MURIA) group workshop and symposium again brought researchers together from across Africa to improve their knowledge of drug utilization (DU) methodologies and exchange ... -
Barriers to the uptake of postexposure prophylaxis among Nairobi-based female sex workers
(University of Nairobi, 2015-09)INTRODUCTION: Female sex workers (FSWs) in sub-Saharan Africa are at a particularly high risk for HIV infection. Postexposure prophylaxis (PEP) is available as part of an HIV care and prevention program through dedicated ... -
Anti-Retroviral Therapy Related Liver Injury A Series of 11 Cases
(University of Nairobi, 2014)Background: HIV Anti-retroviral therapy (ART) related liver injury (ARLI) is associated with elevated liver transaminases (AST/ALT), potential liver failure and death. It is commonly associated with nevirapine. Identification ... -
Reasons for Change of Anti-Retroviral Therapy (ART) Drugs: Local Experience
(University of Nairobi, 2014)Background: Highly active anti-retroviral therapy (HAART) reduces morbidity and mortality in HIV/AIDS infected patients. HAART is used indefinitely and the regimens are changed over the course of treatment due to resistance, ... -
Morbidity and CD4+ Cell Counts at Initial Presentation of a Cohort of HAART-Naive, HIV Positive Kenyan Patients: Implications to Initiating HAART
(University of Nairobi, 2014)Background: Sub-Saharan Africa with under 10% of the worldfs total population accounts for 60-70% of all HIV/AIDS cases. While these patients require HAART to manage the disease, HAART is not universally available. Majority ... -
CD4+ Cell Response to Anti-Retroviral Therapy (ARTS) In Routine Clinical Care Over One Oear Oeriod in a Cohort of HAART Naive, HIV Positive Kenyan Patients
(University of Nairobi, 2014)Background: Untreated HIV/AIDS leads to severe immune depletion with opportunistic infections and other co-morbidities. Highly active anti-retroviral ... -
Diabetes Mellitus/HIV Interphase: A Series of 10 Cases
(University of Nairobi, 2014)Background: Evidence shows that the use of protease inhibitors (PIs) in HIV/AIDS patients leads to the development of diabetes mellitus. Some degree of insulin resistance has also been noted in HIV infected patients not ... -
Cholangiopathy in a Co-Hort of HIV Positive Kenyan Patients
(University of Nairobi, 2014)Background: AIDS (acquired immunodeficiency syndrome) related cholangiopathy results from the inflammation of biliary tree and gall bladder. It is an uncommon manifestation of advanced HIV/AIDS that was associated with ... -
Pyomyositis in HIV: A Series of 12 Cases
(University of Nairobi, 2014)Background: Pyomyositis is a bacterial infection of the large skeletal muscles presenting with muscle pain and swelling. It is commonly seen in the tropics but is being recognised more in end-stage HIV/AIDS. In HIV-associated ... -
Use of mobile learning technology among final year medical students in Kenya
(University of Nairobi, 2015)Introduction Mobile phone penetration has increased exponentially over the last decade as has its application in nearly all spheres of life including health and medical education. This study aimed at assessing the use of ... -
Effect of daily antenatal iron supplementation on plasmodium infection in Kenyan women a randomized clinical trial
(University of Nairobi, 2015)Importance Anemia affects most pregnant African women and is predominantly due to iron deficiency, but antenatal iron supplementation has uncertain health benefits and can increase the malaria burden. Objective To ... -
Host Genetic and Viral Determinants of HIV-1 RNA Set Point among HIV-1 Seroconverters from Sub-Saharan Africa
(University of Nairobi, 2015-09-03)ABSTRACT We quantified the collective impact of source partner HIV-1 RNA levels, human leukocyte antigen (HLA) alleles, and innate re- sponses through Toll-like receptor (TLR) alleles on the HIV-1 set point. Data came ...