Faculty of Health Sciences (FHS): Recent submissions
Now showing items 1501-1520 of 10385
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Molecular signatures of immune activation and epithelial barrier remodeling are enhanced during the luteal phase of the menstrual cycle: implications for HIV susceptibility
(University of Nairobi, 2015)Variable infectivity and transmissibility of HIV/SHIV has been recently associated with the menstrual cycle, with particular susceptibility observed during the luteal phase in non-human primate models and ex vivo human ... -
Wheeze as an adverse event in pediatric vaccine and drug randomized controlled trials: A systematic review.
(University of Nairobi, 2015-08-25)INTRODUCTION: Wheeze is an important sign indicating a potentially severe adverse event in vaccine and drug trials, particularly in children. However, there are currently no consensus definitions of wheeze or associated ... -
The role of regulatory T cells in chronic and acute viral infections
(University of Nairobi, 2008)Regulatory T cells, a subset of CD4+ T lymphocytes, play a pivotal role in the maintenance of the balance between the tissue-damaging and protective effects of the immune response. These cells have immunosuppressive function ... -
A new pterocarpan from the leaves of Abrus precatorius L..
(University of Nairobi, 2015-07-17)A pterocarpan, 2,3,4,8-tetramethoxy-6a,11a-dihydro-6H-benzo[4,5]furo[3,2-c]chromene-7,9-diol (compound 1) was isolated from the dichloromethane extract of the leaves of Abrus precatorius L. The structure of the compound ... -
Mobile phone text messages for improving adherence to antiretroviral therapy (ART): a protocol for an individual patient data meta-analysis of randomised trials
(University of Nairobi, 2013)Introduction Mobile phone text messaging is emerging as an important tool in the care of people living with HIV; however, reports diverge on its efficacy in improving adherence to antiretroviral therapy (ART), and little ... -
Progress in policy issues to improve oral health in Africa
(University of Nairobi, 2004) -
Trichomonas vaginalis infection: can we afford to do nothing?
(University of Nairobi, 2008)For more than a century following its initial description in 1836, Trichomonas vaginalis was considered to be either a harmless vaginal colonizer or simply a minor nuisance [1]. This view may have been sustained by the ... -
Role of anthropology in young infant feeding
(University of Nairobi, 2015-08)Background : Infant feeding is crucial for growth and development of the child . It varies from one context to another including maternal HIV infection. Anthropologists examine infant ... -
A 15-year study of the impact of community antiretroviral therapy coverage on HIV incidence in Kenyan female sex workers.
(University of Nairobi, 2015-07)OBJECTIVE: To test the hypothesis that increasing community antiretroviral therapy (ART) coverage would be associated with lower HIV incidence in female sex workers (FSWs) in Mombasa District, Kenya. DESIGN: Prospective ... -
A phase I double blind, placebo-controlled, randomized study of the safety and immunogenicity of electroporated HIV DNA with or without interleukin 12 in prime-boost combinations with an Ad35 hiv vaccine in healthy hiv-seronegative African Adults.
(University of Nairobi, 2015-08)BACKGROUND: Strategies to enhance the immunogenicity of DNA vaccines in humans include i) co-administration of molecular adjuvants, ii) intramuscular administration followed by in vivo electroporation (IM/EP) and/or ... -
Factors associated with uncontrolled hypertension among renal transplant recipients attending nephrology clinics in Nairobi, Kenya.
(University of Nairobi, 2015)Objective. To determine the factors associated with poor blood pressure control among renal transplant recipients in a resource-limited setting. Methods. A cross-sectional study was carried out on renal transplant recipients ... -
Knowledge on HPV vaccine and cervical cancer facilitates vaccine acceptability among school teachers in Kitui County, Kenya.
(University of Nairobi, 2015-08-12)Background Vaccines against human papillomavirus (HPV) infection have the potential to reduce the burden of cervical cancer. School-based delivery of HPV vaccines is cost-effective and suc- cessful uptake depends on ... -
Immunohistochemical localization of anterior pituitary cell types of vervet monkey (Chlorocebus aethiops) following sub-chronic cathinone exposure.
(University of Nairobi, 2015)ETHNOPHARMACOLOGICAL RELEVANCE: Khat (Catha edulis) contains cathinone, an active principal that is customarily used as a psychostimulant that wards off fatigue and to some extent used as an aphrodisiac. AIM OF ... -
Factors influencing uptake of contraceptive implants in the immediate postpartum period among HIV infected and uninfected women at two Kenyan District Hospitals.
(University of Nairobi, 2015)BACKGROUND: Family planning is a cost effective strategy for prevention of mother to child transmission of HIV and reduction of maternal/infant morbidity and mortality. Contraceptive implants are a safe, effective, long ... -
HIV-1 protease inhibitor drug resistance in Kenyan antiretroviral treatment-naive and -experienced injection drug users and non-drug users.
(University of Nairobi, 2015)BACKGROUND: Although injection drug use drives antiretroviral drug resistance, the prevalence of protease inhibitor (PI) resistance among Kenyan IDUs remains undetermined. We, therefore, explored PI resistance mutations ... -
Water access and sustainable rural livelihoods: A c ase of Elementaita Division in Nakuru County, Kenya
(University of Nairobi, 2015-01-12)This study assessed water factors that impact susta inable rural livelihoods in Elementaita Division, N akuru County. Problem of water access remains a multi-million cha llenge for families in rural areas and this had ... -
Determinants of quality of life among gynaecological cancer patients on follow up at a referral Hospital in Kenya
(University of Nairobi, 2015-06-08)Various factors influence the quality of life (QOL) in cancer patients. This study sought to determine the predictors and factors associated with quality of life among g ynaecological cancer patients on ... -
High fluoride levels in some Kenyan beverages: a health risk.
(University of Nairobi, 1990)A cross section of 93 Kenyan products were analysed for fluoride levels using an F ion-specific electrode. The beverages consisted of 6 pure fruit juices, 25 "ready to drink" fruit juices, 11 "concentrated" fruit juices, ... -
The development of the secondary palate: update on concepts and mechanisms.
(University of Nairobi, 1993)Facial cleft is of multifactorial aetiology, and primary prevention will depend upon a thorough understanding of the developmental mechanisms involved and how they may be disturbed in cleft palate. It is therefore imperative ...