Faculty of Health Sciences (FHS): Recent submissions
Now showing items 1801-1820 of 10385
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Suppression of T-cell proliferative response in Plasmodium falciparum malaria patients - preliminary results
(University of Nairobi, 1989)Suppression of T-cell proliferative responses to P. falciparum specific antigen and mitogens is reported. T-cells derived from malaria patients were co-cultured with P. falciparum antigen or mitogens and the T-cell activity ... -
Albendazole, mebendazole and levamisole
(University of Nairobi, 1987)The activity, mode of action, clinical pharmacology, adverse effects, dosages and clinical use of albendazole (against nematodes and hydatids), and mebendazole and levamisole (against nematodes) are briefly reviewed. The ... -
Assessing partnership linkages for health workforce and research capacity building in Kenya; Lessons learned
(University of Nairobi, 2015)Strategic partnerships across key stakeholders are critical to effectively roll out large scale health system interventions. Leveraging existing networks to develop stronger connections between partners can lead to more ... -
Surveillance for respiratory health care–associated infections among inpatients in 3 Kenyan hospitals, 2010-2012
(University of Nairobi, 2014)Although health care–associated infections are an important cause of morbidity and mortality worldwide, the epidemiology and etiology of respiratory health care–associated infections (rHAIs) have not been documented in ... -
Trends and correlates of HIV testing amongst women : lessons learnt from Kenya : original research
(University of Nairobi, 2013)Background: A majority of women in Kenya do not know their HIV status and are therefore unable to take preventive measures or medication in order to prolong their lives. Objectives: This study investigates the key ... -
Antenatal care and pregnancy outcomes in a safe motherhood health voucher system in rural Kenya, 2007–2013
(University of Nairobi, 2015)Setting: A rural private health facility, Ruby Medical Centre (RMC), participating in a safe motherhood health voucher system for poor women in Kiambu County, Kenya. Objectives: Between 2007 and 2013, to determine 1) ... -
The Expression Analysis of Hexokinase 1 Gene in the Pumwani Commercial Sex Worker Cohort, Nairobi, Kenya
(University of Nairobi, 2014)Background: Altered susceptibility to HIV-1 infection has been observed in a commercial sex worker (CSW) cohort in Nairobi, Kenya, where a subset of women are classified as HIV-1 exposed yet seronegative (HESN). A gene ... -
Low expression of activation and inhibitory molecules on NK cells and CD4+ T cells Is associated with viral control
(University of Nairobi, 2015)Chronic HIV-1 infection induces severe immune alterations, including hyperactivation, exhaustion, and apoptosis. In fact, viral control has been associated with low frequencies of these processes. Here, we evaluated the ... -
Nevirapine resistance in previously nevirapine-unexposed HIV-1 infected Kenyan infants initiating early antiretroviral therapy.
(University of Nairobi, 2015)Nevirapine (NVP) resistance occurs frequently in infants following NVP use in prevention of mother-to-child transmission (PMTCT) regimens. However, among previously NVP-unexposed infants treated with NVP-ART, the development ... -
Moving towards Routine Evaluation of Quality of Inpatient Pediatric Care in Kenya.
(University of Nairobi, 2015)BACKGROUND: Regular assessment of quality of care allows monitoring of progress towards system goals and identifies gaps that need to be addressed to promote better outcomes. We report efforts to initiate routine ... -
High-grade spindle cell sarcoma of the heart: a case report and review of literature
(University of Nairobi, 2015-03)Primary cardiac spindle cell sarcomas are extremely rare and have poor prognosis. Complete surgical resection represents the only treatment option proven to work. We report a case of a 28-year-old man who was referred to ... -
Integration of mental health into primary care and community health working in Kenya: context, rationale, coverage and sustainability
(University of Nairobi, 2010)Integration of mental health into primary care is essential to meet population needs yet faces many challenges if such projects are to achieve impact and be sustainable in low income countries alongside other competing ... -
HIV-1 Drug Resistance Mutations Among Infants Born to HIV-Positive Mothers in Busia, Kenya
(University of Nairobi, 2014)To determine HIV-1 subtypes and transmitted HIV-1 drug-resistant mutations among HIV-1-positive children born to HIV-positive mothers in Busia County, blood samples were collected from 53 children aged between 6 weeks and ... -
High Prevalence of Genetically Similar HIV-1 Recombinants among Infected Sex Workers in Nairobi, Kenya
(University of Nairobi, 2008)HIV-1, a highly diverse infectious agent, shows the greatest sequence diversity in highly exposed individuals, including greater levels of recombination. HIV-1 diversity in Nairobi, Kenya was examined in 240 individuals, ... -
Acute compartment syndrome
(University of Nairobi, 2015)Acute compartment syndrome (ACS) of the lower limb is a potentially disruptive complication that must be recognized early and appropriate action taken to avoid multiple complications. It commonly occurs in closed fractures ... -
Human immunodeficiency virus type 1 clade a and d neurotropism: molecular evolution, recombination, and coreceptor use
(University of Nairobi, 2001)Human immunodeficiency virus type 1 (HIV-1) non-B clade viral infections of the brain have not been studied to date. Among nine AIDS patients from Nairobi, Kenya, infected with HIV-1 A (N = 5) or D (N = 4) clade strains, ... -
Differential expression of two plant-like enolases with distinct enzymatic and antigenic properties during stage conversion of the protozoan parasite Toxoplasma gondii
(University of Nairobi, 2001)The protozoan parasite Toxoplasma gondii differentially expresses two distinct enolase isoenzymes known as ENO1 and ENO2, respectively. To understand differential gene expression during tachyzoite to bradyzoite conversion, ... -
Characterisation and expression of single domain ATP binding cassette protein homologues of the lymphocyte transforming protozoan parasite Theileria parva. Paras
(University of Nairobi, 2001)Two distinct genes encoding single domain, ATP-binding cassette transport protein homologues of Theileria parva were cloned and sequenced. Neither of the genes is tandemly duplicated. One gene, TpABC1, encodes a predicted ... -
Genomic polymorphisms in Theileria parva. In: Genome analysis of protozoan parasites
(University of Nairobi, 1992) -
Enhancement and inhibition of the growth of F38 and related Mycoplasmas by bacterial products
(University of Nairobi, 1986)