Faculty of Health Sciences (FHS): Recent submissions
Now showing items 2501-2520 of 10387
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Mucosal Th17 cell function is altered during HIV infection and is an independent predictor of systemic immune activation.
(University of NairobiDepartment of Medical Microbiology, 2013-09)Mucosal Th17 cells maintain the gut epithelial barrier and prevent invasion by luminal bacteria through a delicate balance of immunosuppressive and proinflammatory functions. HIV infection is characterized by mucosal Th17 ... -
A joint model for longitudinal continuous and time-to-event outcomes with direct marginal interpretation
(WileyCollege of Health Sciences, 2013)Joint modeling of various longitudinal sequences has received quite a bit of attention in recent times. This paper proposes a so-called marginalized joint model for longitudinal continuous and repeated time-to-event outcomes ... -
The role of dendritic cells in driving genital tract inflammation and HIV transmission risk: Are there opportunities to intervene?
(University of NairobiDepartment of Medical Microbiology, 2013-11-26)Effective prevention of new HIV infections will require an understanding of the mechanisms involved in HIV acquisition. HIV transmission across the female genital tract is the major mode of new HIV infections in sub-Saharan ... -
Phase 2A dose and route study of a DNA prime MVA boost vaccine candidate
(University of NairobiSchool of Medicine, 2005) -
Male, Mobile, and Moneyed: Loss to Follow-Up vs. Transfer of Care in an Urban African Antiretroviral Treatment Clinic.
(University of NairobiDepartment of Medical Microbiology,, 2013-10)OBJECTIVES: The purpose of this study was to analyze characteristics, reasons for transferring, and reasons for discontinuing care among patients defined as lost to follow-up (LTFU) from an antiretroviral therapy (ART) ... -
Pharmacokinetics and clinical effects of phenytoin in children with malaria and convulsions
(University of NairobiSchool of Medicine, 2002) -
A qualitative and quantitative study of medical leadership and management: experiences, competencies, and development needs of doctor managers in the United Kingdom
(University of NairobiSchool of Public Health, 2011)Health-care systems need strong leadership if they are to be sustainable and responsive to the health needs of the future. There is little empirical and theoretical literature about how medical managers conceptualize ... -
Occurrence of adverse drug reactions associated with highly active anti-retroviral therapy at Mbagathi District Hospital, Nairobi, Kenya
(University of NairobiSchool of Public Health, 2013)Background: Life-saving highly active anti-retroviral therapy (HAART) has been accompanied by the challenge of incident adverse drug reactions (ADRs). Locally generated data is scanty, inadequately documented, and therefore ... -
Africa: the changing environment and health
(University of NairobiSchool of Public Health, 1992)Like other developing areas of the world, Africa is undergoing social, political, and economic changes. These developmental changes have provided important benefits, but have also produced significant impacts on the ... -
Unmet Need For Induction Of Labor In Africa: Secondary Analysis From The 2004 - 2005 WHO Global Maternal And Perinatal Health Survey (A Cross-sectional Survey)
(University of Nairobi,Department of Obstetrics And Gynaecology, 2004) -
The dengue situation in Afric
(University of NairobiDepartment of Paediatrics, University of Nairobi, 2012-05)Dengue outbreaks and epidemics have been reported in all regions of Africa, and it is believed that all four dengue virus serotypes are in circulation. Available data suggest that dengue is endemic to 34 African countries ... -
Mycoplasma Genitalium infection in sub-Saharan Africa: how big is the problem?
(University of NairobiDepartment of Medical Microbiology, 2013) -
HIV infection deregulates innate immunity to malaria despite combination antiretroviral therapy.
(University of NairobiSandra Rotman Centre for Global Health, University Health Network, University of Toronto, 2013-01)OBJECTIVE: Malaria and HIV-1 adversely interact, with HIV-positive individuals suffering higher parasite burdens and worse clinical outcomes. However, the mechanisms underlying these disease interactions are unclear. ... -
Global epidemiology of Trichomonas vaginalis.
(University of NairobiDepartment of Medical Microbiology,, 2013-09)Despite having the highest prevalence of any sexually transmitted infection (STI) globally, there is a dearth of data describing Trichomonas vaginalis (TV) incidence and prevalence in the general population. The lack of ... -
Association Between Alcohol Use and Sexually Transmitted Infection Incidence Among Kenyan Women Engaged in Transactional Sex.
(University of NairobiDepartment of Medical Microbiology, 2013-11)Few prospective studies have evaluated the association between alcohol use and STI acquisition among African women. We examined the association between baseline drinking frequency and STIs in a cohort of Kenyan women ... -
Incident Herpes Simplex Virus Type 2 Infection Increases the Risk of Subsequent Episodes of Bacterial Vaginosis.
(University of NairobiDepartment of Medical Microbiology, 2013-11)Herpes simplex virus type 2 (HSV-2) infected women have a higher prevalence of bacterial vaginosis (BV) compared to HSV-2-seronegative women. To explore the temporal association between these conditions, we evaluated the ... -
The Diagnosis Of Bladder Calculus With Emphasis On Ultrasonography In A Dog: A Case Report
(University of NairobiSchool of medicine, 2013)A 10kg, 5 year old dachshund bitch (case no 36181) was presented to the Universit y of Nairobi Small Animal Clinic (UON, SAC) with a history of hematuria. The patient was mildly dehydrated and dull. Palpation of ... -
Characterization Of Neuraminidase Inhibitor Susceptibility Of Influenza A Isolates Obtained In Kenya, 2008-2011
(University of NairobiSchool of Medicine, 2013)Background: Vaccines and antivirals are the mainstay for mitigation and clinical management of influenza infections. However, due to the ever-changing antigenic profile, vaccine formulations are revised every year to make ... -
Epidemiological and clinical description of human metapneumovirus infectious diseases in Mbagathi District Hospital, Kenya, in 2008
(University of NairobiSchool of Medicine, 2013)Background: Human metapneumovirus (hMPV), a recently identified respiratory virus, is a leading cause of acute respiratory tract infection in children, the elderly, and immune-compromised persons. Studies have been done ... -
The epidemiology of sexually transmitted co-infections in HIV-positive and HIV-negative African-Caribbean women in Toronto.
(University of NairobiDepartment of Medical Microbiology,, 2013-11)BACKGROUND: HIV disproportionately affects African-Caribbean women in Canada but the frequency and distribution of sexually transmitted infections in this community have not been previously studied. METHODS: We ...