Faculty of Health Sciences (FHS): Recent submissions
Now showing items 2761-2780 of 10387
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Outcome and haemato-toxicity of two chemotherapy regimens for childhood non-Hodgkin's lymphoma in a Kenyan hospital
(Department of Paediatrics, College of Health Sciences, University of Nairobi., 2009)BACKGROUND: Effectiveness and toxicity of childhood cancer treatments have never been evaluated in Kenya since introduction of structured care in the early seventies. OBJECTIVE: To evaluate effectiveness and ... -
Evaluation of urine CCA assays for detection for detection of Schistosoma mansoni infection in Western Kenya
(University of NairobiCollege of Health Science, 2011-01)Although accurate assessment of the prevalence of Schistosoma mansoni is important for the design and evaluation of control programs, the most widely used tools for diagnosis are limited by suboptimal sensitivity, slow ... -
Association of the gene polymorphisms IFN-gamma +874, IL-13 -1055 and IL-4 -590 with patterns of reinfection with Schistosoma mansoni.
(University of NairobiCollege of Health Science, 2009)BACKGROUND: The immunologic findings that most consistently correlate with resistance in human schistosomiasis are high levels of IgE and low levels of IgG4. We have genotyped gene and promoter polymorphisms of cytokines ... -
Identification of cytokeratin 18 as a biomarker of mouse and human hepatosplenic schistosomiasis.
(University of NairobiCollege of Health Science, 2011-02)Previously, we demonstrated unique protein expression patterns in 20-week-Schistosoma mansoni-infected CBA/J mice with moderate splenomegaly syndrome (MSS) or hypersplemomegaly syndrome (HSS). To better understand the ... -
The hyperimmunoglobulin E syndrome--a neutrophil chemotactic defect reversible by histamine H2 receptor blockade?
(College of Health Sciences, University of Nairobi, 1980) -
Schistosomiasis among young children in Usoma, Kenya
(University of NairobiCollege of Health Science, 2011-05)Although schistosomiasis burden is greatest among school-age children (SAC) (6-15 years of age), infection among preschool-age children (PSAC) (1-5 years), may be underestimated in endemic areas. We conducted a cross-sectional ... -
Geographical distribution of schistosomiasis and soil-transmitted helminths among school children in informal settlements in Kisumu City, Western Kenya.
(University of NairobiSchool of Public Health, 2011-10)This cross-sectional study determined the prevalence and distribution of schistosome and soil-transmitted helminth (STH) infections among 1,308 children aged 10-18 years in 34 primary schools in 8 informal urban settlements ... -
Practical therapeutics: psychotherapy.
(KMADepartment of Pyschiatry, 1984) -
You cannot prevent a disease; you only treat diseases when they occur: knowledge, attitudes and practices to water-health in a rural Kenyan community.
(University of NairobiSchool of Public HealthSchool of Public Health, 2011-06)OBJECTIVE: Almost 1 billion individuals lack access to improved water supplies, with 2.6 billion lacking adequate sanitation. This leads to the propagation of multiple waterborne diseases. The objective of this study was ... -
Alcoholism.
(1977) -
Scaling up paediatric HIV care with an integrated, family-centred approach: an observational case study from Uganda.
(College of Health Sciences, University of Nairobi, 2013)Family-centred HIV care models have emerged as an approach to better target children and their caregivers for HIV testing and care, and further provide integrated health services for the family unit's range of care needs. ... -
Microsomal drug-metabolizing enzymes in the olive baboon (Papio anabis).
(College of Health Sciences, University of Nairobi, 1975) -
Detection of putative adduct with fluorescence characteristics identical to 2,3-dihydro-2-(7'-guanyl)-3-hydroxyaflatoxin B1 in human urine collected in Murang'a district, Kenya.
(Oxford JournalsCollege of Health Sciences, University of Nairobi, 1983)Food samples collected in Murang'a district, Kenya are known to be contaminated with a mycotoxin, aflatoxin B1 (AFB), and a positive correlation exists between the dietary intake of AFB and the incidence of liver cancer. ... -
Detection of 8,9-dihydro-(7'-guanyl)-9-hydroxyaflatoxin B1 in human urine.
(College of Health Sciences, University of Nairobi, 1985)A possible role of aflatoxin B1 (AFB) in the etiology of human liver cancer has been suggested from several epidemiological studies. This has been based upon the association between consumption of AFB-contaminated food and ... -
Aflatoxin exposure measured by urinary excretion of aflatoxin B1-guanine adduct and hepatitis B virus infection in areas with different liver cancer incidence in Kenya.
(College of Health Sciences, University of Nairobi, 1987)Two major etiological agents, hepatitis B virus and aflatoxin B1, are considered to be involved in the induction of liver cancer in Africa. In order to elucidate any synergistic effect of these two agents we conducted a ... -
Malacological survey and geographical distribution of vector snails for schistosomiasis within informal settlements of Kisumu City, western Kenya.
(University of NairobiSchool of Public Health, 2011-12)BACKGROUND: Although schistosomiasis is generally considered a rural phenomenon, infections have been reported within urban settings. Based on observations of high prevalence of Schistosoma mansoni infection in schools ... -
Amoebic keratitis: a clinicopathological case report.
(BMJCollege of Health Sciences, University of Nairobi, 1978)A 22-year-old farmer with recurrent corneal erosions and keratoiritis underwent a penetrating keratoplasty. Investigations carried out on the corneal disc revealed an amoebic keratitis, which is considered to be a very ... -
Integrated community-directed intervention for schistosomiasis and soil transmitted helminths in western Kenya - a pilot study.
(University of NairobiSchool of Public Health, 2012-08)BACKGROUND: Schistosome and soil-transmitted helminth (STH) infections are recognized as major global public health problems, causing severe and subtle morbidity, including significant educational and nutritional effects ... -
Study of case-finding for pulmonary tuberculosis in outpatients complaining of a chronic cough at a district hospital in Kenya.
(University of NairobiCollege of Health Sciences, 1984-06)This investigation is the fifth in a series of case-finding studies in Kenya. It explores the potential for case-finding by the identification of persons with suspected tuberculosis (persons with a cough for 1 month or ... -
Schistosoma mansoni morbidity among school-aged children:a SCORE project in Kenya
(University of NairobiSchool of Public Health, 2012-11)Schistosomiasis control programs aim to reduce morbidity but are evaluated by infection prevalence and intensity reduction. We present baseline cross-sectional data from a nested cohort study comparing indicators of morbidity ...