Faculty of Health Sciences (FHS): Recent submissions
Now showing items 3141-3160 of 10387
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Antibodies And Mediators Of Immunity-validation Of A Modified Commercial Enzyme-linked Immunosorbent Assay For Detection Of Human Immunodeficiency Virus Type 1 Immunoglobulin G Antibodies In Saliva
(Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya;, 2001) -
he cost of supplying formula feed to HIV-1 infected women as an intervention against vertical transmission. Journal of Clinical
(Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya, 1999) -
Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 523 transcytosis across human epithelial cells.
(Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya;, 2000)Abstract HIV-1-specific IgA has been described in the genital tract and plasma of HIV-1 highly exposed, persistently seronegative (HEPS) individuals, and IgA from these sites has been shown to neutralize HIV-1. This ... -
Reduced HIV-1 long terminal repeat transcription in subjects with protective interferon regulatory factor-1 genotype: A potential mechanism mediating resistance to infection by HIV-1
(Department of Microbiology, University of Nairobi, Nairobi, KenyaNational Microbiology Laboratories, Public Health Agency of Canada, Winnipeg, Manitoba, CanadaDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada, 2010)We previously described the polymorphism in the interferon regulatory factor-1 (IRF-1) gene as a novel correlate of resistance to HIV-1 infection in a Kenyan female sex worker cohort. However, the underlying mechanisms ... -
Cell phones: tightening the communication gap in resource-limited antiretroviral programmes
(Departments of Medical Microbiology, University of Manitoba, Manitoba, CanadaDepartment of Medical Microbiology, University of Nairobi, Nairobi, Kenya, 2006)Stepping up telecommunications technology in resource-limited healthcare settings has been included as a World Health Organization/UNAIDS priority [1]. Wireless communications in the form of mobile (cellular) phones have ... -
Disseminated Mycobacterium avium Infection Among HIV-Infected Patients in Kenya
(Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya;, 1995)Summary: Previous studies from Africa have been unable to identify disseminated Mycobacterium avium complex (MAC) infection in patients with advanced human immunodeficiency virus (HIV) infection. We performed myco-bacterial ... -
Mucosal IgA in exposed, uninfected subjects: evidence for a role in protection against HIV infection
(Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya;MRC Immunology Group, Institute of Molecular Medicine, Oxford, UKDepartment of Medical Microbiology, University of Manitoba, WinnipegDepartment of Clinical Virology, Karolinska Institute, Stockholm, Sweden., 2001) -
Anti-HLA Alloantibody Is Found in Children But Does Not Correlate with a Lack of HIV Type 1 Transmission from Infected Mothers
(Department of Immunology, University of Toronto, Toronto, Canada M5S 1A8.The Toronto Hospital, Toronto, Canada M5G 1X5.Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya.Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada R3T 2N2.Department of Medicine, University of Toronto, Toronto, Canada M5S 1A8.Mount Sinai Hospital, Toronto, Canada M5G 1X5., 1998)Searching for mechanisms of natural resistance to HIV infection with which to guide HIV vaccine design, we have examined antibody responses to HLA class I antigens in children of HIV-1-infected mothers. Anti-HLA antibodies ... -
The pattern of acute pancreatitis at Kenyatta National Hospital (KNH): retrospective study.
(University of NairobiCollege of Health science, 1988) -
Association of Chlamydia trachomatis Heat-Shock Protein 60 Antibody and HLA Class II DQ Alleles
(Department of Medical Microbiology, University of Nairobi, 1999)A total of 113 female commercial sex workers had individual alleles for HLA class II genes determined by using labeled sequence-specific oligonucleotide probes to hybridize to polymerase chain reaction products of amplified ... -
Renal function in patients with sickle cell anaemia and sickle cell trait in Kenya
(Department of Haematology/Oncology, University of Nairobi, 1995) -
HIV Type 1 Resistance in Kenyan Sex Workers Is Not Associated with Altered Cellular Susceptibility to HIV Type 1 Infection or Enhanced β-Chemokine Production
(Department of Medical Microbiology, University of Nairobi, 1998)A small group of women (n = 80) within the Nairobi-based Pumwani Sex Workers Cohort demonstrates epidemiologic resistance to HIV-1 infection. Chemokine receptor polymorphisms and β-chemokine overproduction have been among ... -
The female condom and STDs: design of a community intervention trial
(ScienceDirectFamily Health International, Research Triangle Park, NC USAUniversity of Nairobi, Department of Medical Microbiology, Nairobi, KenyaFamily Health International, Nairobi, Kenya., 2000)OBJECTIVES: The main purpose of this study is to compare sexually transmitted disease (STD) prevalence in cohorts of women with and without access to female condoms. METHODS: Six matched pairs of communities were ... -
Theileria parva: Isolation of macroschizonts from in vitro propagated lymphoblastoid cells of cattle
(ScienceDirectInternational Laboratory for Research on Animal Diseases, P.O. Box 30709, Nairobi, KenyaDepartment of Medical Microbiology, University of Nairobi, 1981)A method for purifying macroschizonts of Theileria parva from bovine lymphoblastoid cells, propagated in vitro, was developed. This method involved three steps. First, the macroschizonts were liberated by disrupting host ... -
Acute myeloid leukaemia in adults
(University of NairobiCollege of Health science, 1997) -
Breast cancer: early diagnosis.
(University of NairobiCollege of Health science, 2000) -
Experience with vincristine - associated neurotoxicity
(University of NairobiCollege of Health science, 2001)OBJECTIVES: To evaluate the frequency and severity of occurrence of vincristine-associated neurotoxicity. DESIGN: A retrospective case series study. SETTING: Hurlingham Oncology Clinic, Nairobi. SUBJECTS: ... -
Sequence and peptide-binding motif for a variant of HLA-A*0214 (A*02142) in an HIV-1-resistant individual from the Nairobi Sex Worker cohort
(Springer-VerlagDepartment of Medicine, University of Toronto, Toronto, Canada,Department of Microbiology, Mount Sinai Hospital, Room 1484, 600 University Ave., Toronto, Ontario, M5G 1X5, Canada,Department of Microbiology, University of Nairobi, Nairobi, Kenya,Department of Medical Microbiology University of Manitoba, Winnipeg, CanadaDepartment of Immunology, University of Toronto, Toronto, Canada,, 2001)As part of the ongoing study of natural HIV-1 resistance in the women of the Nairobi Sex Workers' study, we have examined a resistance-associated HLA class I allele at the molecular level. Typing by polymerase chain reaction ... -
Intracluster correlation of STD prevalence in a community intervention trial in Kenya
(ScienceDirectFamily Health International, PO Box 13950, Research Triangle Park, NC 27709, USADepartment of Medical Microbiology, University of NairobiFamily Health International, Nairobi, KenyaEscuda de Estadística, Facultad de Ciencias Económicas, Universidad de Costa Rica, San José, Costa Rica, 1999)This study is a cluster-randomised, community intervention trial to measure the impact of female condom introduction on STD prevalence among Kenyan agricultural workers. The intracluster correlation coefficient of baseline ... -
The need for a national cancer policy in Malawi
(University of NairobiCollege of Health science, 2008)Cancer is causing a lot of suffering and death in Africa but is not considered a major health problem in Africa. This needs to change. Cancer should be given equal emphasis to HIV/AIDS, tuberculosis (TB) and Malaria. A ...