Isolation and structural elucidation of compounds from the non-alkaloidal extract of nicandra physaloides and the antimicrobial activity of withanicandrin
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Date
2013Author
Mukungu, N A
Abuga, KO
Mungai, NN
Bosire, KO
Karumi, E W
Language
enMetadata
Show full item recordAbstract
The aerial parts of Nicandra physaloides plant collected from Kenyatta National
Hospital grounds were dried and subjected to acid-base extraction and partitioned
to obtain alkaloidal and non-alkaloidal extracts. The non-alkaloidal extract yielded
three compounds; withanicandrin, β-sitosterol and stigmasterol after column
chromatography. Withanicandrin exhibited antifungal activity against
Saccharomyces cerevisiae and Candida albicans but lacked antibacterial activity.
Citation
Mukungu, N. A., Abuga, K. O., Mungai, N. N., Bosire, K. O., & Karumi, E. W. (2015). Isolation and structural elucidation of compounds from the non-alkaloidal extract of Nicandra physaloides and the antimicrobial activity of withanicandrin. East and Central African Journal of Pharmaceutical Sciences, 16(2013), 49-53.Publisher
University of Nairobi
Collections
- Faculty of Health Sciences (FHS) [10385]