Screening for tuberculosis in pregnancy: do we need more than a symptom screen? Experience from western Kenya
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Date
2013Author
Kosgei, R J
Szkwarko, D
Callen, S
Gichangi, P
Temmerman, M
Kihara, A B
Sitienei, J J
Cheserem, E J
Ndavi, P M
Reid, A J
Carter, E J
Language
enMetadata
Show full item recordAbstract
Objectives:
1) To
explore the utility of tuberculosis (TB)
symptom screening for symptoms of
⩾
2 weeks’ duration
in a routine setting, and 2) to compare differences in TB
diagnosis between human immunodeficiency virus (HIV)
infected and non-HIV-infected pregnant women in west-
ern Kenya.
Design:
Comparative cross-sectional study among preg-
nant women with known HIV status screened for TB from
2010 to 2012, in Eldoret, western Kenya.
Results:
Of 2983 participants, respectively 34 (1%),
1488 (50.5%) and 1461 (49.5%) had unknown, positive
and negative HIV status. The median age was respectively
30 years (interquartile range [IQR] 26–35) and 26 years
(IQR 24–31) in HIV-infected and non-infected participants.
A positive symptom screen was found in respectively
8% (119/1488) and 5% (67/1461) of the HIV-infected
and non-infected women. The median CD4 count at en-
rolment was 377 cells/
μ
l (IQR 244–530) for HIV-infected
women. One non-HIV-infected patient was sputum-
p
ositive. For HIV-infected women, TB was presumptively
treated in 1% (16/1488) based on clinical symptoms and
chest X-ray. Cumulatively, anti-tuberculosis treatment was
offered to 0.6% (17/2949) of the participants.
Conclusion:
This study does not seem to demonstrate the
utility of TB symptom screening questionnaires in a rou-
tine setting among pregnant women, either HIV-infected
or non-infected, in western Kenya.
Citation
Kosgei, R. J., Szkwarko, D., Callens, S., Gichangi, P., Temmerman, M., Kihara, A. B., ... & Carter, E. J. (2013). Screening for tuberculosis in pregnancy: do we need more than a symptom screen? Experience from western Kenya. Public Health Action, 3(4), 294-298.Publisher
University of Nairobi
Collections
- Faculty of Health Sciences (FHS) [10385]