dc.contributor.author | Takken, Willem | |
dc.contributor.author | Loon, Joop J A van | |
dc.contributor.author | Wolfgang, Richard M | |
dc.contributor.author | Mweresa, Collins K | |
dc.contributor.author | Derycke, Jean-Luc | |
dc.contributor.author | Vandendaele, Patrice | |
dc.contributor.author | Carreira, Ana S | |
dc.contributor.author | Homan, Tobias | |
dc.contributor.author | Holdinga, Maarten | |
dc.contributor.author | Omusula, Philemon | |
dc.contributor.author | Menger, David J | |
dc.date.accessioned | 2015-06-18T06:15:54Z | |
dc.date.available | 2015-06-18T06:15:54Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Menger, David J., Philemon Omusula, Maarten Holdinga, Tobias Homan, Ana S. Carreira, Patrice Vandendaele, Jean-Luc Derycke et al. "Field Evaluation of a Push-Pull System to Reduce Malaria Transmission." (2015): e0123415. | en_US |
dc.identifier.uri | http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123415 | |
dc.identifier.uri | http://hdl.handle.net/11295/85067 | |
dc.description.abstract | Malaria continues to place a disease burden on millions of people throughout the tropics, especially in sub-Saharan Africa. Although efforts to control mosquito populations and reduce human-vector contact, such as long-lasting insecticidal nets and indoor residual spraying, have led to significant decreases in malaria incidence, further progress is now threatened by the widespread development of physiological and behavioural insecticide-resistance as well as changes in the composition of vector populations. A mosquito-directed push-pull system based on the simultaneous use of attractive and repellent volatiles offers a complementary tool to existing vector-control methods. In this study, the combination of a trap baited with a five-compound attractant and a strip of net-fabric impregnated with micro-encapsulated repellent and placed in the eaves of houses, was tested in a malaria-endemic village in western Kenya. Using the repellent delta-undecalactone, mosquito house entry was reduced by more than 50%, while the traps caught high numbers of outdoor flying mosquitoes. Model simulations predict that, assuming area-wide coverage, the addition of such a push-pull system to existing prevention efforts will result in up to 20-fold reductions in the entomological inoculation rate. Reductions of such magnitude are also predicted when mosquitoes exhibit a high resistance against insecticides. We conclude that a push-pull system based on non-toxic volatiles provides an important addition to existing strategies for malaria prevention. | en_US |
dc.language.iso | en | en_US |
dc.title | Field Evaluation of a Push-Pull System to Reduce Malaria Transmission | en_US |
dc.type | Article | en_US |
dc.type.material | en | en_US |