| dc.contributor.author | Achola, K J | |
| dc.contributor.author | Mwangi, J W | |
| dc.contributor.author | Munenge, R W | |
| dc.contributor.author | Mwaura, A M | |
| dc.date.accessioned | 2015-07-26T07:37:32Z | |
| dc.date.available | 2015-07-26T07:37:32Z | |
| dc.date.issued | 1996 | |
| dc.identifier.citation | Pharmaceutical Biology, 1996, Vol. 34, No. 2 : Pages 141-144 | en_US |
| dc.identifier.uri | http://informahealthcare.com/doi/abs/10.1076/phbi.34.2.141.13190 | |
| dc.identifier.uri | http://hdl.handle.net/11295/88824 | |
| dc.description.abstract | A 70% methanol aerial part extract of Vernonia glabra caused a fall in blood pressure in anaesthetised rats. After the 50 µg dose, systolic, diastolic, and mean blood pressures decreased by 56%, 66%, and 61% respectively below the baseline levels. The adrenaline-like activity of the extract was not antagonised by L(-) propranolol on isolated rabbit heart. The extract caused contraction on the isolated rabbit ileum and was abolished with atropine, suggesting the presence of a compound with acetylcholine-like activity. The extract on isolated guinea pig ileum caused contraction which was dose related. | en_US |
| dc.language.iso | en | en_US |
| dc.title | Pharmacological Activities of Vernonia glabra | en_US |
| dc.type | Article | en_US |
| dc.type.material | en | en_US |
