dc.contributor.author | Ogeto, John O | |
dc.date.accessioned | 2016-06-29T16:15:56Z | |
dc.date.available | 2016-06-29T16:15:56Z | |
dc.date.issued | 1984 | |
dc.identifier.uri | http://hdl.handle.net/11295/96605 | |
dc.description.abstract | The initial aim of this work was to synthesise both Diazepam ( 7 chloro- 1,3 dihydro- I methyl- 5 phenyl 2H 14 benzodiazepin-2-one) and Oxazepam ( 7 chloro- 1,3 dihydro- 3 hydroxy- 5 phenyl- 2H 14 benzo- diazepin-2-one)
However due to the failure to obtain, in good tine, commercial supplies of the intermediate 2- amino- 5 chloro- benzophenone ( 2 amino- 5 chlorophenyl- phenyl methanone ) it was not possible to synthesise the benzodiazepine nucleus.
Hence this work mainly covers the synthesise of the 2 amino- 5 chloro benzophenone intermediate employing those chemicals that were available. | en_US |
dc.language.iso | en | en_US |
dc.publisher | University of Nairobi | en_US |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/us/ | * |
dc.title | A Study Of Some Of The Reactions Involved In The Synthesis Of The 14 Benzodiazepines | en_US |
dc.type | Thesis | en_US |
dc.description.department | a
Department of Psychiatry, University of Nairobi, ; bDepartment of Mental Health, School of Medicine,
Moi University, Eldoret, Kenya | |