University of Nairobi Institutional Repository: Recent submissions
Now showing items 2861-2880 of 115145
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Increasing African Genomic Data Generation and Sharing to Resolve Rare and Undiagnosed Diseases in Africa: a Call-to-action by the H3africa Rare Diseases Working Group
(University of Nairobi, 2022)The rich and diverse genomics of African populations is significantly underrepresented in reference and in diseaseassociated databases. This renders interpreting the Next Generation Sequencing (NGS) data and reaching a ... -
Diagnostic accuracy of the syndromic management of four STIs among individuals seeking treatment at a health centre in Nairobi, Kenya: a cross-sectional study
(University of Nairobi, 2021)Introduction: the syndromic approach to the management of sexually transmitted diseases (STIs) is recommended in areas without adequate laboratory support. We assessed the diagnostic accuracy of this approach in diagnosing ... -
Novel PhoH-encoding vibriophages with lytic activity against environmental Vibrio strains
(University of Nairobi, 2021)Cholera is a devastating diarrheal disease that accounts for more than 10% of children's lives worldwide, but its treatment is hampered by a rise in antibiotic resistance. One promising alternative to antibiotic therapy ... -
COVID-19 risk factors: The curious case of Africa's governance and preparedness Author links open overlay panel
(University of Nairobi, 2021)COVID-19 is now established in Africa, and requires appropriate prioritization of resources and customized control measures. Although there have been lower than predicted number of COVID-19 cases (6,839,159 (3.4% of global ... -
Antimicrobial Resistance Profiles and Genes of Staphylococci Isolated from Mastitic Cow’s Milk in Kenya
(University of Nairobi, 2021)Increasing numbers of potentially zoonotic multidrug-resistant (MDR) staphylococci strains, associated with mastitis in dairy cows, are being reported globally and threaten disease management in both animal and human ... -
In Vitro Antimicrobial and Antiproliferative Activities of the Root Bark Extract and Isolated Chemical Constituents of Zanthoxylum Paracanthum Kokwaro (Rutaceae)
(University of Nairobi, 2020)Abstract: Zanthoxylum paracanthum Kokwaro (Rutaceae) is an endemic Kenyan and Tanzanian plant used in folk medicine by local populations. Although other Zanthoxylum species have been studied, only Z. paracantum stem ... -
Prioritization of Loita Maasai Medicinal Plants for Conservation
(University of Nairobi, 2021)Medicinal plants provide biodiversity-based ecosystem services including health to many communities around the world and therefore, medicinal plant conservation is vital for sus- tainability. Here, we identify medicinal ... -
The Chemosystematics of the Genus Zanthoxylum L. (Rutaceae) in Kenya
(Kaigongi MM, Lukhoba CW. "The chemosystematics of the genus Zanthoxylum L.(Rutaceae) in Kenya." Biochemical Systematics and Ecology. 2021; 98, :104319., 2021)ackground and aim There is currently a significant taxonomic confusion in the genus Zanthoxylum which has a wide application in Kenyan herbal medicine. The significance of proper identification/classification of medicinal ... -
High Multiple Carriage and Emergence of Streptococcus Pneumoniae Vaccine Serotype Variants in Malawian Children
(University of Nairobi, 2015)Background: Carriage of either single or multiple pneumococcal serotypes (multiple carriage) is a prerequisite for developing invasive pneumococcal disease. However, despite the reported high rates of pneumococcal carriage ... -
Cytotoxic Flavonoids From the Seeds of Dracaena Steudneri Engl Against Leukemia Cancer Cell Lines
(University of Nairobi, 2022)Background: Leukemia is the most common type of childhood cancer. Numerous flavonoids isolated from plants have been reported as potential chemotherapeutic agents against malignant growth while taking care of healthy c ... -
Antiplasmodial and Antimicrobial Activities of Ent- Abietane Diterpenoids From the Roots of Suregada Zanzibariensis
(University of Nairobi, 2022)The root extract ofSuregada zanzibariensisBaill. afforded six previ-ously describedent-abietane diterpenoids, namely 7-oxo-ent-abieta-5(6),8(14),13(15)-trien-16,12-olide (1), mangiolide (2),8,14b:11,12a-diepoxy ... -
Potential Antibacterial Pharmaceuticals From the Flora of Africa
(University of Nairobi, 2022)The present chapter highlights the antibacterial potential of nine highly active compounds isolated from the African medicinal plants: 8,8-bis-(dihydroconiferyl)- diferulate, buesgenine, candidone, diospyrone, ferruginin ... -
Phytochemistry and Antibacterial Potential of the Genus Garcinia
(University of Nairobi, 2022)Species of the genus Garcinia (Clusiaceae) have been used for centuries in different folk medicine for the treatment of several ailments, as well as food supplements. Evidence from previous studies has demonstrated a ... -
Chemical Constituents From the Stem Bark of Ficus Thonningii and Their Chemotaxonomic Significance
(University of Nairobi, 2022)Background of the Study: Tropical plants of the Ficus genus (Moraceae) are among the earliest fruit trees that humans have cultivated. Since ancient times, many folk medicines have used species of this genus to treat a ... -
Laboratory and Field Performance of Metarhizium Anisopliae Isolate Icipe 41 for Sustainable Control of the Invasive Fall Armyworm Spodoptera Frugiperda (Lepidoptera: Noctuidae)
(University of Nairobi, 2022)To overcome the negative impacts of invasive fall armyworm (FAW), this study assessed the laboratory and field efficacy of aqueous and oil-based formulations of Metarhizium anisopliae ICIPE 41 as an alternative source ... -
Antibacterial Activities of Thirteen Naturally Occuring Compounds From Two Kenyan Medicinal Plants: Zanthoxylum Paracanthum (Mildbr) Kokwaro (Rutaceae) and Dracaena Usambarensis Engl. (Asparagaceae) Against MDR Phenotypes
(University of Nairobi, 2022)The antibacterial potency of thirteen compounds reported from two distinct genera, Zanthoxylum (Rutaceae) and Dracaena (Asparagaceae) against a panel of sensitive and multi-drug resistant Gram-positive and Gram-negative ... -
Utilization of data management and performance of microfinance institutions funding entrepreneurial projects Kisumu County, Kenya
(AJBUMA, 2023-02-20)Data management is the development and execution of architecture, policies, practices and procedures in order to manage the information lifecycle needs of microfinance institutions funding entrepreneurial projects ... -
Effect of Competitive Advantage on the Relationship Between Strategic Leadership and Performance of International Non-governmental Organizations in Kenya
(University of Nairobi, 2021)In developing countries, International Non-Governmental Organizations (INGOs) have taken active and complementary roles in sustainable human development. Despite the role of INGOs in development, the issues of sustainability, ... -
Rules of Engagement: Factors Influencing Employees Engagement in Insurance Companies
(University of Nairobi, 2021)Organizations are striving to find better ways of engaging their employees since many organizations have realised that workers are the most imperative resource for achieving their goals. Several research studies have been ... -
Waste Oil Management by Petroleum Business Operators: an Analysis of the Legal and Institutional Framework
(University of Nairobi, 2018)For years' petroleum products comprising of fuels and motor oils have been used in different industries in Kenya notably by Petroleum Business Operators. These products are harmful to the environment in their processed ...