Synthesis of Vernolamides from Vernonia galamensis Oil under Varied Conditions and Their Antimicrobial Activities
Yusuf, A. O.
Bhatt, B. M.
Gitu, P. M.
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The oil extracted from the seeds of Vernonia galamensis ssp. nairobensis was reacted with 1,6-diaminohexane and 1,8-diaminooctane using a 1:3 molar ratio of vernonia oil to amine to give the corresponding vernolamides. Varied temperatures and solvents were applied. The vernolamides exhibited antibacterial activity against gram-positive (Bacillus subtilis) and on gram-negative (Escherichia coli) bacteria. The vernolamides did not show any antifungal activity