|dc.description.abstract||This study was conducted over a period of ten months
from April, 1989 to February, 1990.
The study included a total of 160 cases. Of these, 58
were sickle cell anaemia patients of whom 32 were females,
50 were sickle cell trait cases of whom 32 were females,
and 52 were controls of whom 32 were females.
The ages of the patients with sickle cell anaemia ranged
between 2 years and 36 years with a mean of 15 ± 7.2
(S.D.) years, the ages of the sickle cell trait cases
from 4 years to 44 years with a mean of 18.5 ± 10.3 (S.D.)
years, and the ages of the controls between 4 years and
35 years with a mean of 16.5 ± 8.4 (S.D.) years. The
age and sex variation between the three groups were not
significant (P > 0.05).
Clinical features and some biochemical indices of renal
function, together with the prevalence of urinary tract
infection in patients with sickle cell anaemia, sickle
cell traits and controls were studied.
Polyuria, nocturia, polydypsia and enuresis were noted
more frequently in sickle cell anaemia patients and sickle
cell trait cases than in controls, and this was statistically
significant (P < 0.05) in both cases. There was no
statistical difference in these clinical parameters between
sickle cell anaemia patients and sickle cell trait cases.
Enuresis was more common,among the younger age group
in both groups, with 54% of all the sickle cell anaemia
patients with enuresis and all the sickle cell trait
cases with enuresis being in the age group 5 - 10 years.||en
Department of Psychiatry, University of Nairobi, ; bDepartment of Mental Health, School of Medicine,
Moi University, Eldoret, Kenya||