Some clinico-histopathologic aspects of kaposi's sarcoma in patients with and without the Acquired Immune Deficiency Syndrome
This is a five year retrospective study of Kaposi's Sarcoma as seen at Kenyatta .National Hospital. A dramatic change in epidemiology and cl inical presentation is observed. This include a lower M:F ratio of 4.5:1, a younger age group, changes in ethnic distribution and an increase in the lyrnphadenopathic form of the disease. There i sad i ve r sit y 0 f c 1i n i c a I pre s en tat ion i n AIDS - Ka p 0 s i ' s Sarcoma patients with the neoplasm being widely disseminated, however limb involvement is not uncorrmon. All forms of Kaposi's Sarcoma were seen dur i ng th is per i od . Histologically slit forming type predominated in AIDS-Kaposi's Sarcoma lesions. Other significant differences on histology include the degree of inflammatory cell infiltrate (p<O.OS), presence of sclerosis (p<O.OI) and the presence of necrosis or ulceration (p<O.OS).