CCR5, RANTES, and SDF-1 polymorphisms and mother-to-child HIV-1 transmission

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Date
2010
Author
Katz, David A
John-Stewart, Grace C
Richardson, Barbra A
Majiwa, Maxwell
Mabuka, Jennifer M
Lohman-Payne, Barbara
Farquhar, Carey
Type
Article
Language
en
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Abstract
Among 288 HIV-1-infected, breastfeeding women who received zidovudine prophylaxis and were followed with their infants in Nairobi, we found no associations between maternal genetic polymorphisms in CCR5 (59029G/A, 59353T/C, 59356T/C, 59402G/A), RANTES (−403G/A), and SDF-1 (3′801G/A) and mother-to-child HIV-1 transmission; plasma, cervical, and breastmilk viral loads; or breastmilk chemokine concentrations.
URI
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922909/
http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/16188
Citation
Int J Immunogenet. 2010 August; 37(4): 301–305.
Publisher
Department of Paediatrics
Subject
Chemokines
CCR5
RANTES
HIV-1
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