Correlation of CD4 counts and CD4/CD8 ratio with HIV-infection associated oral manifestations
| dc.contributor.author | Butt, FM | |
| dc.contributor.author | Vaghela, VP | |
| dc.contributor.author | Chindia, ML | |
| dc.date.accessioned | 2013-06-25T06:36:17Z | |
| dc.date.available | 2013-06-25T06:36:17Z | |
| dc.date.issued | 2007-08 | |
| dc.description.abstract | BACKGROUND: The relationship between oral lesions arising from HIV infection and CD4/CD8 cell ratios is of relevance in clinical assessment of immune suppression. OBJECTIVE: To correlate the prevalence of oral manifestations arising from HIV infection and the levels of CD4/CD8 cell ratios. DESIGN: A cross-sectional study. SETTING: Kenyatta National Hospital, Nairobi, Kenya. SUBJECTS: Two hundred and seven HIV-infected patients in medical wards were recruited in the study. RESULTS: Seventy eight (37.7%) were male and 129 (62.3%) female, with an age range of 18-73 years (mean=34.81 years). Oral manifestations encountered with highest prevalence in the oral cavity included: hyperplastic candidosis (labial mucosa) 15%, erythematous candidosis (gingival) 5%, angular cheilitis 32.4%, herpes simplex (corner of the mouth) 0.5%, persistent oral ulceration (labial mucosa) 0.5%, Parotid enlargement 2% and Kaposis sarcoma (hard/soft palate) 2.9%. CONCLUSION: The prevalence of oral manifestations was higher with low CD4 count <200 cell/mm3 and mean CD4/CD8<0.39(95%CI 0.32-0.48) | en |
| dc.identifier.citation | East Afr Med J. 2007 Aug;84(8):383-8. | en |
| dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/17970007 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/39372 | |
| dc.language.iso | en | en |
| dc.publisher | University of Nairobi | en |
| dc.title | Correlation of CD4 counts and CD4/CD8 ratio with HIV-infection associated oral manifestations | en |
| dc.type | Article | en |
| local.publisher | Department of Oral and Maxillofacial Surgery, College of Health Sciences, University of Nairobi. | en |