Orbital Tumours: A radiological and histologic correlation

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Muiri, GW

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Thesis

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University of Nairobi

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Thesis

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Introduction Orbital tumours constitute a heterogeneous array of benign and malignant lesions. These tumours lead to morbidity and mortality in affected patients. Diagnosis of orbital tumours depends on appropriate imaging and histology results. Objectives The main objective of this study was to determine the level of correlation between computed tomography diagnosis and histologic diagnosis of commonly occurring orbital tumours in KNH. Methods This was a one year retrospective cross sectional hospital based study done from June 2007 to June 2008 at Kenyatta National Hospital (KNH). It included all patients seen in KNH during the period of study with the relevant computed tomography and histology results. The imaging modality evaluated was Computed Tomography (CT). A correlation was then made between computed tomography and histologic diagnosis and the results presented with the aid of tables, pie charts and graphs. Results A total of 35 cases were recorded over a one year period and were later analyzed. The most prevalent tumour overall was Retinoblastoma 20%, followed by squamous cell carcinoma II% and Rhabdomyosarcoma 9%. The overall mean age was 20.6 years. In at least 68.6% of cases the radiological and histologic diagnosis correlated. Overall there was no statically significant gender predominance. Conclusion. There is a high level of correlation between computed tomography and histopathology diagnosis of orbital turn ours especially taking into account that computed tomography was mainly done on patients whose diagnosis could not be made clinically and on Ultrasonography (U/S). The high level of correlation is essential for optimal patient management.

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Masters Of Medicine In Diagnostic Radiology, University of Nairobi,2009

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