Bacterial vaginosis in HIV-infected women induces reversible alterations in the cervical immune environment
Bacterial vaginosis in HIV-infected women induces reversible alterations in the cervical immune environment
Loading...
Date
Authors
Rebbapragada, Anuradha
Howe, Kathryn
Wachihi, Charles
Pettengell, Christopher
Sunderji, Sherzana
Huibner, Sanja
Ball, T. Blake
Plummer, Francis A.
Jaoko Walter G.
Kaul, Rupert
Type
Article
Journal Title
Journal ISSN
Volume Title
Publisher
Type
Article
Abstract
Bacterial vaginosis (BV) has been associated with
increased HIV cervicovaginal shedding. We hypothesized that this might relate to BV-associated increases in mucosal activated CD4+ T cells, which could enhance local HIV replication BV induces significant and reversible alterations in cervical immune cell populations and local inflammatory cytokines
that would be expected to enhance local HIV replication
Description
Keywords
Altered vaginal flora,, Bacterial vaginosis,, Genital tract,, HIV,, Inflammation,, Mucosal immunology,, Transmission
Citation
J Acquir Immune Defic Syndr Volume 49, Number 5, December 15, 2008