Baboon vaginal microbial flora.
Date
2016Author
JA, Obiero
Waititu, KK
Mulei, I
Omar, FI
Jaoko, W
Mwethera, PG
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
BACKGROUND:
Knowledge of the composition of vaginal microbial ecosystem is essential for understanding the etiology, prevention, and treatment of vaginal diseases. A baboon model has been used to provide detailed understanding of reproductive physiology and immunology applicable to women. However, little is known about the composition of its vaginal microbial ecosystem.
METHODS:
Gram stain and Nugent scores were used for assessment of baboon vaginal microbial flora. Biochemical identification and analysis of isolates were performed using the api(®) kits and identification software.
RESULTS:
Species of Lactobacilli, Staphylococci, Clostridia, Bacilli, Corynebacteria, Gram-negative rods, other Gram-positive rods, cocci and Candida, were isolated. Healthy vaginal microbiota consisted mainly of lactobacillus morphotypes. Animals with high Nugent scores had increased number of Gram-positive cocci and variable rods, with increased number of Gram-negative morphotypes.
CONCLUSIONS:
The baboon vaginal microbiota is heterogeneous in terms of species composition and is typified by a scarcity of lactobacilli.
URI
https://www.ncbi.nlm.nih.gov/pubmed/27198467http://onlinelibrary.wiley.com/doi/10.1111/jmp.12217/full
http://hdl.handle.net/11295/100641
Citation
Obiero, Jael A., et al. "Baboon vaginal microbial flora." Journal of medical primatology 45.3 (2016): 147-155.Publisher
University of Nairobi
Rights
Attribution-NonCommercial-NoDerivs 3.0 United StatesUsage Rights
http://creativecommons.org/licenses/by-nc-nd/3.0/us/Collections
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