Phylogenetics in plant biotechnology: principles, obstacles and opportunities for the resource poor
Date
2007Author
Ochieng, Joel W.
Muigai, Anne W. T.
Ude, George N
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Phylogenetic inference has become routine for most studies of genetic variation among plant taxa.
However, inferring phylogenies can be confounded by both biological and computational or statistical
complexities, resulting in misleading evolutionary hypotheses. This is particularly critical because the
“true tree” can only truly be known in exceptional circumstances. Moreover, selecting appropriate
marker(s), characters, sample sizes and the appropriate reconstruction methods offers a challenge to
most evolutionary geneticists. Textbooks are generic (and sometimes outdated), and in resource poor
labs, they may altogether be inaccessible. In this review, we take the worker through the low-down on
reconstructing a phylogeny, review the enigmatic biological and computational problems, and examine
cases where cheaper markers and extremely small sample sizes can recover a reliable phylogeny