Browsing Faculty of Health Sciences (FHS) by Author "Baeten, JM"
Now showing items 1-1 of 1
-
High-dose valacyclovir HSV-2 suppression results in greater reduction in plasma HIV-1 levels compared with standard dose acyclovir among HIV-1/HSV-2 coinfected persons: a randomized, crossover trial.
Mugwanya, K; Baeten, JM; Mugo, NR; Irungu, E; Ngure, K; Celum, C (Infectious Diseases Institute, Makerere University, Kampala, Uganda, 2011)Standard-dose HSV-2 suppressive therapy (acyclovir 400 mg twice daily) reduces plasma HIV-1 levels by 0.25-0.50 log(10) copies/mL. It is not known if higher doses might further suppress HIV-1 levels. METHODS: We enrolled ...