_Between transcriptional Comparison Of The Immune System Of HIV-Exposed Uninfected And HIV-Uninfected Infants In Kilifi,Kenya

Abstract

Vertical transmission of HIV -1 has reduced over the years due to the introduction of prevention mechanism such as HAART obstetrics management and reduced breastfeeding .This has led to a decrease in the HIV infected infant population giving rise to a new termed as the HIV exposed uninfected infants (HEU) ;uninfected infants of HIV positive mothers .The HEU infants has been found to have an increased hospitalization and mortality rate related to the HIV -unexposed uninfected (HUU)infants ;uninfected infants of HIV negative mothers .Whether this is as a result of environmental exposure or intrinsic immunological alteration is not clear .this study focus on the effects of HIV exposure on the immune system of the HEU infant that may led to the immunological alterations........