dc.contributor.author | Gakuya, D.W. | |
dc.contributor.author | Mbaria, J.M. | |
dc.contributor.author | Mbithi, Peter Mulwa F | |
dc.contributor.author | Munene, R.W. | |
dc.date.accessioned | 2013-02-23T06:18:45Z | |
dc.date.issued | 2004 | |
dc.identifier.citation | The Kenya Veterinarian VOL. 26 (2004) | en |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/10818 | |
dc.description.abstract | The purpose of this experiment was to evaluate
the bioactivity of extracts of Chrysanthemum
cinerariaefolium Vis., Albizia anthelmintica A.
Broqn, Maerua edulis (Gilg) De Wolf, Maerua
subcordata (Gilg &Bened) De Wolf and Myrsine
africana L. which are used traditionally as
anthelmintic by using brine shrimp lethality test.
Serial dilutions of 1OOO~g/ml, 1OO~g/ml and
1O~g/ml of the extracts were put in five test
tubes. Ten (10) brine shrimp larvae were
immersed into each of the test tubes and the
number surviving after 24 hours counted and the
percentage mortality and LCso for each extract
was determined. C. cinerariaefolium extract (
pyrethrins) was active ( LCso< 1OOO~g/ml) at
LCso of 1.3 ~g/ml while the'" methanol extract of
A. anthelmintica bark was active with LCso of
18~g/ml. The methanol extracts of Maerua
edulis, Maerua subcordata and Myrsine africana
were not active (LCso< 1000~g/ml). The result
indicated that C. cinerareafolium and A.
anthelmintica extracts have bioactivity and is the
basis for their use as anthelmintic by pastoral
communities. Brine shrimp lethality test was
found to be a simple and rapid test and is thus
recommended for similar studies. | en |
dc.language.iso | en | en |
dc.subject | Bioactivity | en |
dc.subject | Traditional | en |
dc.subject | Medicinal Plants | en |
dc.subject | Brine Shrimp Lethality | en |
dc.subject | Test | en |
dc.title | Evaluation of the Bioactivity of some Traditional Medicinal Plants using the Brine Shrimp Lethality Test | en |
dc.type | Article | en |
local.publisher | Department of clinical studies | en |
local.publisher | Department of Public Health, pharmacology and Toxicology | en |