| dc.contributor.author | Wagate, G. Cyrus | |
| dc.contributor.author | Gakuya, Daniel, W. | |
| dc.contributor.author | Nanyingi, Mark, O. | |
| dc.contributor.author | Njonge, Francis, K. | |
| dc.contributor.author | Mbaria, James M | |
| dc.date.accessioned | 2013-02-23T06:56:46Z | |
| dc.date.issued | 2008 | |
| dc.identifier.citation | Mem Inst Oswaldo Cruz, Rio de Janeiro, Vol. 103(7), 2008 | en |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/10830 | |
| dc.description.abstract | Seven medicinal plant extracts traditionally used in Kenya, mainly for management of infectious conditions, were
chosen and screened for their antibacterial activity against Gram-negative (Pseudomonas aeruginosa and Escherichia
coli) and Gram-positive (Bacillus cereus and Staphylococcus aureus) bacteria. Antibacterial activity was tested
using the broth dilution method. Harrisonia abyssinica and Terminalia kilimandscharica extracts showed significant
activity against Gram+ and Gram- bacteria. The methanolic extracts of T. kilimandscharica bark and H. abyssinica
bark and leaves showed minimum inhibitory activity against all tested bacteria, with minimal inhibitory concentrations
ranging from 25-150 mg/mL. Ajuga remota and Amaranthus hybridus, which are lethal to brine shrimp nauplii,
showed significantly lower antibacterial activity than those that were relatively non-toxic. | en |
| dc.language.iso | en | en |
| dc.subject | Antibacterial | en |
| dc.subject | Cytotoxicity | en |
| dc.subject | Medicinal Plants | en |
| dc.title | Antibacterial and cytotoxic activity of Kenyan medicinal plants | en |
| dc.type | Article | en |
| local.publisher | Department of Public Health, pharmacology and Toxicology | en |
| local.publisher | Department of clinical studies | en |
