Synthesis of Vernolamides from Vernonia galamensis Oil under Varied Conditions and Their Antimicrobial Activities
Date
2006Author
Mbugua, M.N.
Yusuf, A. O.
Bhatt, B. M.
Gitu, P. M.
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
The oil extracted from the seeds of Vernonia galamensis ssp. nairobensis was reacted with
1,6-diaminohexane and 1,8-diaminooctane using a 1:3 molar ratio of vernonia oil to amine
to give the corresponding vernolamides. Varied temperatures and solvents were applied. The
vernolamides exhibited antibacterial activity against gram-positive (Bacillus subtilis) and on
gram-negative (Escherichia coli) bacteria. The vernolamides did not show any antifungal
activity
Citation
Journal of the Kenya Chemical Society Vol.3 No.1Publisher
Chemistry
Subject
Vernonia galamensisN-(6-aminohexyl)vemolamide
N-(8aminooctyl)vemolamide
Anti-microbial activities