Synthesis and binding studies of ring constrained glucagon analogues
dc.contributor.author | Mbugua, Martin Njogu | |
dc.date.accessioned | 2013-05-07T08:31:45Z | |
dc.date.available | 2013-05-07T08:31:45Z | |
dc.date.issued | 2007 | |
dc.identifier.citation | Athesis submitted in fulfillment for the Degree of Doctor of Philosophy ofthe University of Nairobi | en |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/19631 | |
dc.description.abstract | The aim of this study was to design and synthesize glucagon antagonists,which alone or in combination with insulin may be of potential therapeutic value in the treatment of Diabetes mellitus.Glucagon and twenty new cyclic glucagon analogues were synthesized using both manual and automated Na-Fmoc solid phase peptide synthetic protocol SPPS). | |
dc.language.iso | en | en |
dc.title | Synthesis and binding studies of ring constrained glucagon analogues | en |
dc.type | Thesis | en |