Kinetic study of acid-catalysed rearrangements of 1,2-oxazines

Abstract

A kinetic study of acid-catalysed rearrangement of 6-ethoxy-5,6- dihydro-3-para-substituted phenyl-4H-l ,2-oxazines (9) in methanol (MeOH), cyanomethane (MeCN) and in dimethylsulfoxide (M~SO) to 3,4-dihydro-2- methoxy-5-parasubstituted phenyl-2H-pyrrole-l-oxides (10) is reported. The substrate oxazines were synthesized by the cycioaddition reaction of 2- bromopara-substituted acetophenone oximes with ethyl vinyl ether in dichloromethane..............