| dc.contributor.author | Heydenreich, Matthias | |
| dc.contributor.author | Muiva, Lois M. | |
| dc.contributor.author | Eyase, Fredrick L. | |
| dc.contributor.author | Akala, Hoseah M. | |
| dc.contributor.author | Wanyama, P. Juma | |
| dc.contributor.author | Yenesew, Abiy | |
| dc.contributor.author | Imbuga, Mabel | |
| dc.contributor.author | Walsh, Douglas S. | |
| dc.contributor.author | Peter, Martin G. | |
| dc.contributor.author | Gitu, Peter M. | |
| dc.contributor.author | Okalebo, Faith A. | |
| dc.date.accessioned | 2013-05-09T08:52:42Z | |
| dc.date.available | 2013-05-09T08:52:42Z | |
| dc.date.issued | 2011 | |
| dc.identifier.citation | Phytochemical Society of Europe | en |
| dc.identifier.other | doi:l0.1016/j.phytoI.2011.02.010 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/20668 | |
| dc.description | Terpurinflavone: An antiplasmodial flavone from the stem of Tephrosia Purpurea | en |
| dc.description.abstract | The stem extract of Tephrosia purpurea showed anti plasmodial activity against the D6 (chloroquinesensitive)
and W2 (chloroquine-resistant) strains of Plasmodium /aldparum with 1(50 values of
10.47 ± 2.22 f.Lg/mland 12.06 ± 2.54 f.Lg/ml,respectively. Anew prenylated flavone, named terpurinflavone,
along with the known compounds lanceolatin A.(-)-semiglabrin and lanceolatin Bhave been isolated from
this extract. The new compound, terpurinflavone, showed the highest anti plasmodial activity with 1(50
values of 3.12 ± 0.28 f.LM(D6) and 6.26 ± 2.66 f.LM(W2). The structures were determined on the basis of
spectroscopic evidence. | en |
| dc.language.iso | en | en |
| dc.publisher | Elsevier B.V. | en |
| dc.subject | Tephrosia, purpurea, Leguminosae, Stem, Flavone, Terpurintlavone, Anriplasmadial | en |
| dc.title | Terpurinflavone: An antiplasmodial flavone from the stem of Tephrosia Purpurea | en |
| dc.type | Article | en |
| local.publisher | Department of Chemistry,University of Nairobi | en |
| local.publisher | United Stares Army Medical Research Unit-Kenya | en |
| local.publisher | Department of Biochemistry, Jomo Kenyatta University of Agriculeure and Technology | en |
| local.publisher | Insrieur fur Chemie, Universitat Potsdam, | en |
| local.publisher | School of Pharmacy, University of Nairobi, | en |
