Anti-giardial activity of gastrointestinal remedies of the Luo of east Africa
Date
1995-04Author
Johns, T
Faubert, GM
Kokwaro, JO
Mahunnah, RJ
Kimanani, EK
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Activity in an in vitro assay with Giardia lamblia provided a test of the validity of a quantitative methodology used in an ethnobotanical survey of the Luo people of the Lake Victoria basin of Kenya and Tanzania. Forty-five taxa of remedies for gastrointestinal problems were reported by four or more independent informants and a log-linear model was used to calculate a statistical measure of informant consensus. Methanolic extracts of 21 of 36 taxa assayed were lethal or inhibited growth of Giardia trophozoites at 1000 ppm; 7 species were lethal at 500 ppm. Non-cathartic species are more likely to be active than cathartics. Lethal species of non-cathartics are reported by informants more frequently than non-lethal species although the lack of statistical significance did not provide satisfactory support for the validity of the quantitative methodology as a predictor of efficacious remedies
URI
http://www.ncbi.nlm.nih.gov/pubmed/7475119http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/29123
Citation
J Ethnopharmacol. 1995 Apr;46(1):17-23.Publisher
University of Nairobi. Department of Botany