dc.contributor.author | Mburu, J N | |
dc.contributor.author | Kamau, J M Z | |
dc.contributor.author | Badamana, M S | |
dc.date.accessioned | 2013-06-11T09:11:48Z | |
dc.date.available | 2013-06-11T09:11:48Z | |
dc.date.issued | 1994 | |
dc.identifier.citation | Mburu, J. N, kamau, J. M, Z & Badamana, M. S(194). Thyroid hormones and metabolic rate during induction of Vitamin B12 deficiency in goats. New Zealand Veterinary Journal;42(5):187-189 | en |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/31370 | |
dc.description | Journal article | en |
dc.description.abstract | Vitamin B12 deficiency was induced in 15 small East African goats by feeding cobalt deficient Chloris guyana hay (containing 0.02 mg of Co/kg dry matter) over a 25week experimental period. Cobalt was supplemented as an oral drench to supply 0.3 g of Co/goat/week to 15 treated goats. At intervals of 3–4 weeks, serum concentrations of Vitamin B12 total thyroxine (TT4), free tetra-iodothyronine (FT4) and free tri-iodothyronine (FT3) were determined by radioimmunoassay, while the rate of resting metabolism was determined by measuring the goats' rate of oxygen consumption.
Serum Vitamin B12 concentration was significantly higher (p<0.01) in cobalt-treated (289.6 ± 40.76 pg/ml) than in control (142.8 ± 28.27 pg/ml) goats. The mean serum TT4 concentration was signifieantly (p<0.01) higher in control (59.0 ± 1.70 nmol/l) than in cobalt-treated (51.6 ± 2.45 nmol/l) goats. However, the levels of FT4, FT3 and the rate of resting metabolism were unaffected by the goats' cobalt status. Furthermore, the goats did not lose weight or become anaemic. | en |
dc.language.iso | en | en |
dc.publisher | Taylor and Francis Group | en |
dc.subject | Thyroid hormones | en |
dc.subject | Metabolic rate | en |
dc.subject | Induction | en |
dc.subject | Vitamin B12 Deficiency | en |
dc.subject | Goats | en |
dc.title | Thyroid hormones and metabolic rate during induction of Vitamin B12 deficiency in goats | en |
dc.type | Article | en |
local.publisher | Department of Animal Production, University of Nairobi | en |
local.publisher | Department of Animal Physiology, University of Nairobi | en |