dc.contributor.author | Weda, EH | |
dc.contributor.author | Otieno, RO | |
dc.contributor.author | Ngotho, JW | |
dc.contributor.author | Bøgh, HO | |
dc.contributor.author | Waruiru, RM | |
dc.date.accessioned | 2013-06-13T08:05:16Z | |
dc.date.available | 2013-06-13T08:05:16Z | |
dc.date.issued | 1996-08 | |
dc.identifier.citation | Trop Anim Health Prod. 1996 Aug;28(3):216-20. | en |
dc.identifier.uri | http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/8888527 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/32798 | |
dc.description.abstract | Forty-nine sheep artificially exposed to a thiabendazole (TBZ) resistant isolate of Haemonchus contortus were assigned to 7 groups of 7 animals each and used to conduct a controlled anthelmintic trial. One group of sheep served as untreated infected controls and 6 groups were treated as follows: closantel, 5.0 mg kg-1; ivermectin, 0.2 mg kg-1; oxfendazole, 5.0 mg kg-1; thiophanate, 50 mg kg-1, levamisole, 7.5 mgkg-1 and thiabendazole, 66 mg kg-1. Eggs per gram of faeces were determined on days 21, 24 and day 34 (10 days post-treatment) after infection and all animals were necropsied for residual worm counts. The calculated efficacies of the treatments against H. contortus as indicated by worm reduction were closantel (100%), ivermectin (99.3%), oxfendazole (35.2%), thiophanate (56.7%), levamisole (98.6%) and thiabendazole (24.3%). The data therefore indicate that the TBZ-resistant isolate of H. contortus used was highly resistant to the 2 benzimidazole (BZ) anthelmintics, oxfendazole and thiophanate. This is the first report in Kenya of a field strain of H. contortus resistant to thiophanate. | en |
dc.language.iso | en | en |
dc.publisher | University of Nairobi. | en |
dc.title | Comparative efficacies of closantel, ivermectin, oxfendazole, thiophanate and levamisole against thiabendazole resistant Haemonchus contortus in sheep | en |
dc.type | Article | en |
local.publisher | Department of Veterinary Pathology and Microbiology, University of Nairobi, Kenya. | en |