Resistance of E. coli strains, recovered from chickens to antibiotics with particular reference to trimethoprim-sulfamethoxazole (septrin).
Date
1994Author
Bebora, L C
Oundo, J O
Yamamoto, H
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Thirty-seven strains of E. coli recovered from cases of septicaemia in chicken were tested for sensitivity to 6 antibiotics. Minimum inhibitory concentration (MIC) determinations done on the strains showed resistance to trimethoprim-sulfamethoxazole (septrin) (100%), ampicillin (62.2%), tetracycline (51.4%), kanamycin (13.5%) and gentamicin (2.7%). All were sensitive to chloramphenicol. Conjugation studies showed easy transfer of the resistance factor for septrin to the recipient sensitive strain, K12F-, a 60 megadalton plasmid was transferred in most of the cases (a number of plasmids moved across to K12F- strains). Septrin was chosen as a referral antibiotic because it is used extensively for treating diarrhoeal cases in children in Kenya. The results expressed the possibility of the chicken being the possible source of the septrin resistance gene (plasmid) for humans, and vice versa.
URI
http://www.ncbi.nlm.nih.gov/pubmed/7821238http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/33520
Citation
Bebora, L. C, Oundo, J. O & Yamamoto, H(1994). Resistance of E. coli strains, recovered from chickens to antibiotics with particular reference to trimethoprim-sulfamethoxazole (septrin). East African Medical Journal; 71(10): 624-7Publisher
Department of Veterinary Pathology, Microbiology and Parasitology, University of Nairobi
Description
Journal article