7a-O-methyldeguelol, a modified rotenoid with an open ring-C, from the roots of Derris trifoliata
Midiwo Jacob O.
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From the acetone extract of the roots of Derris trifoliata an isoflavonoid derivative, named 7a-O-methyldeguelol, a modified rotenoid with an open ring-C, representing a new sub-class of isoflavonoids (the sub-class is here named as rotenoloid), was isolated and characterised. In addition, the known rotenoids, rotenone, deguelin and α-toxicarol, were identified. The structures were determined on the basis of spectroscopic evidence. Rotenone and deguelin were identified as the larvicidal principles of the acetone extract of the roots of Derris trifoliata.
CitationPhytochemistry Volume 66, Issue 6, March 2005, Pages 653–657
Department of Chemistry, University of NairobiDepartment of Zoology, University of Nairobi,Institut für Chemie, Universität Potsdam, P.O. Box 601553, D-14415 Potsdam, Germany