Rotenoid derivatives from Kenyan Millettia and Derris species as larvicidal agents
Date
2000Author
Yenesew, Abiy
Kiplagat, John T
Mushibe, Eluid K
Derese, Solomon
Midiwo, Jacob O
Kabaru, JM
Heydenreich, Matthias
Peter, Martin G
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Rotenone (1), one of the most extensively used natural insecticides, was reported to be highly
toxic to the 4th instar larvae of Aedes aegypti (Abe et al., 1985). The insecticidal activities of
rotenone and some other rotenoids, including deguelin (2) and tephrosin (3) against a variety of
insect species are well known (Fukami and Nakajima, 1971). Commercially, rotenone is
mainly extracted from the roots of Derris species in Asia and Lonchocarpus species in South
America (Fukami and Nakajima, 1971). Rotenone and other flavonoids are also known to occur
in several plants, including Millettia, belonging to the family Leguminosae (Dewick, 1994).
We have studied the larvicidal activities of several rotenoids isolated from Millettia and
Derris species. The structures and larvicidal activities of these rotenoids are reviewed in this
paper.
Citation
11th NAPRECA Symposium Book of Proceedings, Antananarivo, Madagascar Pages 161-168Publisher
Department of Chemistry, University of Nairobi Department of Zoology, University of Nairobi,