Antimicrobial Activities of a New Schizozygane Indoline Alkaloid from Schizozygia coffaeoides and the Revised Structure of Isoschizogaline
Date
2002-04-21Author
Kariba R M.
Houghton P J.
Yenesew Abiy.
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Extracts from Schizozygia coffaeoides showed antimicrobial activity against fungal and bacterial species. Alkaloids isolated using bioassay-guided fractionation were isoschizogaline, schizogynine, and a new indoline alkaloid, 7,8-dehydro-19β-hydroxyschizozygine, shown to be the most active antifungal compound. The structure of isoschizagaline, the only active antibacterial, is revised on the basis of NMR analysis.
URI
http://pubs.acs.org/doi/abs/10.1021/np010298mhttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/34726
http://www.ncbi.nlm.nih.gov/pubmed/11975502
Citation
J. Nat. Prod., 2002, 65 (4), pp 566–569 DOI: 10.1021/np010298m Publication Date (Web): February 21, 2002.Publisher
University of Nairobi Department of Botany and Department of Chemistry,