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dc.contributor.authorYenesew Abiy.
dc.contributor.authorDerese Solomon.
dc.contributor.authorMidiwo Jacob O.
dc.contributor.authorHeydenreich M.
dc.contributor.authorPeter M G.
dc.date.accessioned2013-06-17T08:00:00Z
dc.date.available2013-06-17T08:00:00Z
dc.date.issued2003-10
dc.identifier.citationYenesew, A., Derese, S., Midiwo, J. O., Heydenreich, M. and Peter, M. G. (2003), Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti. Pest. Manag. Sci., 59: 1159–1161. doi: 10.1002/ps.740en
dc.identifier.urihttp://onlinelibrary.wiley.com/doi/10.1002/ps.740/abstract
dc.identifier.urihttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/34775
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pubmed/14561074
dc.description.abstractA crude chloroform extract of seeds of Millettia dura Dunn (Leguminosae) showed high activity (LC50 = 3.5 µg ml−1 at 24 h) against second-instar larvae of the mosquito, Aedes aegypti L (Diptera: Culicidae). The rotenoids, deguelin and tephrosin, isolated from the seeds of this plant also showed potent activities, with LC50 values of 1.6 and 1.4 µg ml−1 at 24 h, respectively. The related rotenoids millettone and millettosin were inactive at 20 µg ml−1. Saturation at the B/C ring junction and the presence of methoxy groups at C-2 and/or C-3 in deguelin and tephrosin appear to be important for the observed larvicidal activity. Copyright © 2003 Society of Chemical Industryen
dc.language.isoenen
dc.publisherUniversity of Nairobien
dc.subjectMillettia dura;Leguminosae;rotenoids;tephrosin;deguelin;Aedes aegypti;larvicidesen
dc.titleEffect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegyptien
dc.typeArticleen
local.publisherDepartment of Chemistry, University of Nairobien


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