Skin irritant diterpene orthoesters of the daphnane type from Peddiea africana and P. Volkensii

dc.contributor.author	Adolf, w
dc.contributor.author	Dossajia, SF
dc.contributor.author	Seip, EH
dc.contributor.author	Hecker, E
dc.date.accessioned	2013-06-17T14:01:52Z
dc.date.available	2013-06-17T14:01:52Z
dc.date.issued	1985
dc.identifier.citation	Phytochemistry Volume 24, Issue 9, 1985, Pages 2047–2049	en
dc.identifier.uri	http://www.sciencedirect.com/science/article/pii/S0031942200831192
dc.identifier.uri	http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/35051
dc.description.abstract	From roots of Peddiea volkensii (Thymelaeaceae) the irritant factors V1 and V2 and from roots of P. africana the irritant factor A1 were isolated. Their structures are the 9,13,14-ortho-(2,4,6-decatrienoates) of 5β-hydroxyresiniferonol-6α,7α-oxide (V1) and of 5β,12β-dihydroxyresiniferonol-6α,7α-oxide (A1) and the 12-O-acetate of the latter (V2). Factors V1 and V2 do not exhibit tumour-promoting activity in the standard initiation-promotion protocol on mouse skin, although V1 is a moderate irritant.	en
dc.language.iso	en	en
dc.publisher	Elsevier	en
dc.subject	Peddiea africana	en
dc.subject	P. volkensii	en
dc.subject	Thymelaeaceae	en
dc.subject	irritants	en
dc.subject	diterpene esters	en
dc.subject	tumour promoters	en
dc.subject	antileukemic activity	en
dc.title	Skin irritant diterpene orthoesters of the daphnane type from Peddiea africana and P. Volkensii	en
dc.type	Article	en
local.publisher	Department of botany, University of Nairobi	en

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