Plasmid Mediated Antimicrobial Resistance In Klebsiela Pneumoniae Isolated From Neonates In A Hospital Ward
Date
1992Author
Nyenze, E
Ilako, D
Kimani, K
Senerwa, Daniel
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Antibiotic neosensitab susceptibility to ten commonly used antibiotics was done on 65 Klebsiella pneumoniae strains isolated from neonates in a nursery ward. All the strains except one were resistant to one or more antibiotic, and more than 0% of the isolates were resistant of 4 or more antibiotics. The isolates carried 18 different antibiotic resistance determinants. The most frequent antibiotic resistance determinants carried by a single resistant isolate were those of trimethoprim-sulfamethoxazole, chloramphenicol, oxytetracycline, ampicilin, and gentamicin which were found in 23 (35.3%) strains. The average number of antibiotic resistances per resistant strain was 4.there was no consistent relationship between plasmid profile group and antibiotic resistance pattern. A spontaneous loss of a 180 MDa plasmid by a resistant strain was accompanied by a loss of resistance to trimethoprim-sulfamethoxazole and oxytetracyline.
URI
http://profiles.uonbi.ac.ke/dsenerwa/publications/plasmid-mediated-antimicrobial-resistance-klebsiela-pneumoniae-isolated-neonathttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/35067
Citation
M, Dr Senerwa Daniel. 1992. Plasmid Mediated Antimicrobial Resistance In Klebsiela Pneumoniae Isolated From Neonates In A Hospital Ward. East African Journal Of Ophthalmology. : Nyenze E, Ilako D, Kimani KPublisher
University of Nairobi, Department of Public Health and Pharmacology