Babesia gibsoni: Identification of an immunodominant, interspersed repeat antigen
Date
2008Author
Jia, Honglin
Terkawi, M. Alaa
Aboge, Gabriel Oluga
Goo, Youn-Kyoung
Zhou, Jinlin
Lee, Eung-Goo
Nishikawa, Yoshifumi
Igarashi, Ikuo
Fujisaki, Kozo
Xuan, Xuenan
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
In this report, an immunodominant antigen called BgIRA from Babesia gibsoni is identified and described. A highly repetitive antigen was screened from a cDNA library. The genomic BgIRA gene exists as single cope gene and contains 10 introns. BgIRA plays a dominant role in the immune response in dogs infected with B. gibsoni. The specificity and sensitivity of the rBgIRA in an ELISA indicated that this antigen might be useful in a diagnostic test.
URI
http://www.sciencedirect.com/science/article/pii/S0014489407001944http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/35892